| Product Number |
ARP34117_T100 |
| Product Page |
www.avivasysbio.com/g22p1-antibody-n-terminal-region-arp34117-t100.html |
| Name |
G22P1 Antibody - N-terminal region (ARP34117_T100) |
| Protein Size (# AA) |
609 amino acids |
| Molecular Weight |
70kDa |
| NCBI Gene Id |
2547 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
X-ray repair complementing defective repair in Chinese hamster cells 6 |
| Alias Symbols |
ML8, KU70, TLAA, CTC75, CTCBF, G22P1 |
| Peptide Sequence |
Synthetic peptide located within the following region: NFKNIYVLQELDNPGAKRILELDQFKGQQGQKRFQDMMGHGSDYSLSEVL |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Sawchuk,D.J., et al., (2004) J. Biol. Chem. 279 (28), 29821-29831 |
| Description of Target |
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. |
| Protein Interactions |
UBC; ELF3; EHF; CHD1L; SUMO2; SUMO3; MDM2; EMD; ATRX; RPA3; RPA2; RPA1; PCNA; EED; PRPF40A; SUPT5H; ST13; SET; PLOD2; PIN1; NARS; MSH2; RPSA; JUP; IMPDH1; MSH6; GART; DPYSL3; CTNNA1; SAMHD1; ATP6V1B2; GANAB; SWAP70; WBP4; HYOU1; FARSB; RANBP3; CUL2; CSDE1 |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-XRCC6 (ARP34117_T100) antibody |
| Blocking Peptide |
For anti-XRCC6 (ARP34117_T100) antibody is Catalog # AAP34117 (Previous Catalog # AAPP05590) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human G22P1 |
| Uniprot ID |
Q6FG89 |
| Protein Name |
X-ray repair cross-complementing protein 6 |
| Sample Type Confirmation |
XRCC6 is supported by BioGPS gene expression data to be expressed in HepG2 |
| Protein Accession # |
NP_001460 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_001469 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
XRCC6 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Dog: 93%; Guinea Pig: 86%; Horse: 86%; Human: 100%; Mouse: 93%; Rabbit: 86%; Rat: 93% |
| Image 1 | Human kidney
 | Human kidney |
|
| Image 2 | Human Liver
 | Human Liver |
|
| Image 3 | Human HepG2
 | WB Suggested Anti-G22P1 Antibody Titration: 0.6ug/ml
ELISA Titer: 1:312500
Positive Control: HepG2 cell lysateXRCC6 is supported by BioGPS gene expression data to be expressed in HepG2 |
|
| Image 4 | Human Heart
 | Rabbit Anti-XRCC6 Antibody
Catalog Number: ARP34117
Paraffin Embedded Tissue: Human cardiac cell
Cellular Data: Epithelial cells of renal tubule
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X |
|
