GRHL3 Antibody - C-terminal region (ARP33196_P050)

Data Sheet
 
Product Number ARP33196_P050
Product Page www.avivasysbio.com/grhl3-antibody-c-terminal-region-arp33196-p050.html
Name GRHL3 Antibody - C-terminal region (ARP33196_P050)
Protein Size (# AA) 509 amino acids
Molecular Weight 57kDa
NCBI Gene Id 57822
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Grainyhead-like 3 (Drosophila)
Description
Alias Symbols SOM, VWS2, TFCP2L4
Peptide Sequence Synthetic peptide located within the following region: SGVKGCLLSGFRGNETTYLRPETDLETPPVLFIPNVHFSSLQRSGGAAPS
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Ting,S.B., et al., (2003) Biochem. J. 370 (PT 3), 953-962
Description of Target GRHL3 is a member of the grainyhead family of transcription factors. GRHL3 interacts with leader-binding protein 32 (LBP-32) and brother of mammalian grainyhead (BOM), and may function as a transcription factor during development. Multiple transcript variants encoding distinct isoforms have been identified for this gene. This gene encodes a member of the grainyhead family of transcription factors. The encoded protein interacts with leader-binding protein 32 (LBP-32) and brother of mammalian grainyhead (BOM), and may function as a transcription factor during development. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Additional transcript variants have been described, but their biological nature has not been determined.
Protein Interactions PRMT6; PRMT5; PRMT1; GRHL1; GRHL3; GRHL2;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-GRHL3 (ARP33196_P050) antibody
Blocking Peptide For anti-GRHL3 (ARP33196_P050) antibody is Catalog # AAP33196 (Previous Catalog # AAPP04233)
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human GRHL3
Uniprot ID Q8TE85-4
Protein Name Grainyhead-like protein 3 homolog
Publications

Yu, Z., Mannik, J., Soto, A., Lin, K. K. & Andersen, B. The epidermal differentiation-associated Grainyhead gene Get1/Grhl3 also regulates urothelial differentiation. EMBO J. 28, 1890-903 (2009). 19494835

Protein Accession # NP_937817
Purification Affinity Purified
Nucleotide Accession # NM_198174
Tested Species Reactivity Human
Gene Symbol GRHL3
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Application WB, ChIP, IHC
Predicted Homology Based on Immunogen Sequence Cow: 92%; Dog: 92%; Guinea Pig: 92%; Horse: 92%; Human: 100%; Mouse: 100%; Rabbit: 92%; Rat: 92%
Image 1
Human Placenta
WB Suggested Anti-GRHL3 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:12500
Positive Control: Human Placenta
Image 2
Human 786-0 Whole Cell
Host: Rabbit
Target Name: GRHL3
Sample Tissue: Human 786-0 Whole Cell
Antibody Dilution: 1ug/ml
 

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