| Product Number |
ARP32896_T100 |
| Product Page |
www.avivasysbio.com/hes6-antibody-c-terminal-region-arp32896-t100.html |
| Name |
HES6 Antibody - C-terminal region (ARP32896_T100) |
| Protein Size (# AA) |
224 amino acids |
| Molecular Weight |
25kDa |
| NCBI Gene Id |
55502 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
Hairy and enhancer of split 6 (Drosophila) |
| Alias Symbols |
HES-6, bHLHb41, bHLHc23, C-HAIRY1 |
| Peptide Sequence |
Synthetic peptide located within the following region: PPGPGDDLCSDLEEAPEAELSQAPAEGPDLVPAALGSLTTAQIARSVWRP |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Kang,S.A., (2005) Biochem. Biophys. Res. Commun. 332 (1), 33-36 |
| Description of Target |
HES6 belongs to a subfamily of basic helix-loop-helix transcription factors that includes Drosophila Hairy and Enhancer of split genes. Like other members of the family, HES6 features the WRPW motif which is consisted just of four amino acids at its C-terminus. It is expressed by both undifferentiated and differentiated cells and is an inhibitor of Hes1. HES6 supports Mash1 activity and promotes cell differentiation. |
| Protein Interactions |
TWIST1; CREBBP; TLE1; HES1; CSNK2A1; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-HES6 (ARP32896_T100) antibody |
| Blocking Peptide |
For anti-HES6 (ARP32896_T100) antibody is Catalog # AAP32896 (Previous Catalog # AAPP03920) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human HES6 |
| Uniprot ID |
Q96HZ4 |
| Protein Name |
Transcription cofactor HES-6 |
| Protein Accession # |
NP_061115 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_018645 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
HES6 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Dog |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Dog: 86%; Human: 100%; Mouse: 79%; Rat: 86% |
| Image 1 | Human Pancreas
 | Human Pancreas |
| | Image 2 | Transfected 293T
 | WB Suggested Anti-HES6 Antibody Titration: 1.25ug/ml
Positive Control: Transfected 293T |
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