| Product Number |
ARP32406_P050 |
| Product Page |
www.avivasysbio.com/sirt7-antibody-c-terminal-region-arp32406-p050.html |
| Name |
SIRT7 Antibody - C-terminal region (ARP32406_P050) |
| Protein Size (# AA) |
400 amino acids |
| Molecular Weight |
45kDa |
| NCBI Gene Id |
51547 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Sirtuin 7 |
| Alias Symbols |
SIR2L7 |
| Peptide Sequence |
Synthetic peptide located within the following region: DVMRLLMAELGLEIPAYSRWQDPIFSLATPLRAGEEGSHSRKSLCRSREE |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Mahon,P.C., et al., (2000) Biochem. Biophys. Res. Commun. 273 (2), 793-798 |
| Description of Target |
SIRT7 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. SIRT7 is included in class IV of the sirtuin family. |
| Protein Interactions |
DDB1; VPRBP; APP; NOL6; YTHDC2; DDX31; RBM15; ANAPC1; NSD1; NOC3L; UBE2O; RBM25; CCAR2; CHD8; BEND3; PHRF1; DHX37; NUFIP2; CGN; XPO5; LRRC47; BIRC6; WDR18; THOC2; NUP107; REXO4; DDX24; XAB2; UGGT1; ZC3HAV1; YLPM1; NKRF; CCT5; SNW1; DHX30; DIS3; PUF60; COP |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-SIRT7 (ARP32406_P050) antibody |
| Blocking Peptide |
For anti-SIRT7 (ARP32406_P050) antibody is Catalog # AAP32406 (Previous Catalog # AAPP03401) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human SIRT7 |
| Uniprot ID |
Q9NRC8 |
| Protein Name |
NAD-dependent protein deacetylase sirtuin-7 |
| Protein Accession # |
NP_057622 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_016538 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
SIRT7 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100% |
| Image 1 | Human Jurkat
 | WB Suggested Anti-SIRT7 Antibody Titration: 0.2-1 ug/ml
Positive Control: Jurkat cell lysate |
|
