Product Number |
ARP32388_T100 |
Product Page |
www.avivasysbio.com/sirt3-antibody-middle-region-arp32388-t100.html |
Name |
SIRT3 Antibody - middle region (ARP32388_T100) |
Protein Size (# AA) |
399 amino acids |
Molecular Weight |
44kDa |
NCBI Gene Id |
23410 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1.0 mg/ml |
Gene Full Name |
Sirtuin 3 |
Alias Symbols |
SIR2L3 |
Peptide Sequence |
Synthetic peptide located within the following region: SGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPKPFFTLAKELYP |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Bellizzi,D., et al., (2005) Genomics 85 (2), 258-263 |
Description of Target |
SIRT3 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. |
Protein Interactions |
SIRT5; SKP2; UBC; HSPD1; CMYA5; PGAP1; RIF1; NCAPD2; HERC2; TTF2; UQCRH; UGDH; HSP90B1; SNTB1; SBF1; HSPA9; HSPA5; HSPA4; HSPA1L; GRN; ATP5B; ATP5A1; SIRT4; tat; XRCC6; FOXO3; DNM1L; PEX5; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-SIRT3 (ARP32388_T100) antibody |
Blocking Peptide |
For anti-SIRT3 (ARP32388_T100) antibody is Catalog # AAP32388 (Previous Catalog # AAPP03378) |
Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human SIRT3 |
Uniprot ID |
Q9NTG7 |
Protein Name |
NAD-dependent protein deacetylase sirtuin-3, mitochondrial |
Protein Accession # |
NP_036371 |
Purification |
Protein A purified |
Nucleotide Accession # |
NM_012239 |
Tested Species Reactivity |
Human |
Gene Symbol |
SIRT3 |
Predicted Species Reactivity |
Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Dog: 100%; Guinea Pig: 83%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 92%; Rat: 100%; Yeast: 77%; Zebrafish: 85% |
Image 1 | Human HepG2
| WB Suggested Anti-SIRT3 Antibody Titration: 2.5ug/ml ELISA Titer: 1:312500 Positive Control: HepG2 cell lysate |
|