NFATC4 Antibody - N-terminal region (ARP32040_P050)

• Product Number: ARP32040_P050
• Name: NFATC4 Antibody - N-terminal region (ARP32040_P050)
• Protein Size (# AA): 902 amino acids
• Molecular Weight: 95kDa
• NCBI Gene Id: 4776
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Gene Full Name: Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
• Alias Symbols: NFAT3, NF-AT3, NF-ATC4
• Peptide Sequence: Synthetic peptide located within the following region: RGPEDSWLLLSAPGPTPASPRPASPCGKRRYSSSGTPSSASPALSRRGSL
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Reference: Zhang,H., (2005) J. Biol. Chem. 280 (52), 43188-43197
• Description of Target: NFATC4 is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family of nuclear factors of activated T cells also participate in the formation of this complex. NFATC4 plays a role in the inducible expression of cytokine genes in T cells, especially in the induction of the IL-2 and IL-4.The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family of nuclear factors of activated T cells also participate in the formation of this complex. The product of this gene plays a role in the inducible expression of cytokine genes in T cells, especially in the induction of the IL-2 and IL-4.
• Protein Interactions: ANKRD28; Dlg4; NR1I2; MAPK9; MAPK8; JUP; GPR22; CCNG1; LPIN1; CEBPA; GATA4; YWHAZ; MAPK14; CREBBP; YWHAQ;
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Blocking Peptide: For anti-NFATC4 (ARP32040_P050) antibody is Catalog # AAP32040 (Previous Catalog # AAPP02942)
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NFATC4
• Uniprot ID: Q14934
• Protein Name: Nuclear factor of activated T-cells, cytoplasmic 4
• Protein Accession #: NP_004545
• Purification: Affinity Purified
• Nucleotide Accession #: NM_004554
• Tested Species Reactivity: Mouse
• Gene Symbol: NFATC4
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
• Application: WB
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
• Image 1: Mouse Pancreas
  
  Host: Mouse
  Target Name: NFATC4
  Sample Tissue: Mouse Pancreas
  Antibody Dilution: 1ug/ml
• Image 2: r-NFATC4
  
  WB Suggested Anti-NFATC4 Antibody Titration: 0.2-1 ug/ml
  Positive Control: Transfected 293T