| Product Number |
ARP31834_P050 |
| Product Page |
www.avivasysbio.com/nr5a1-antibody-middle-region-arp31834-p050.html |
| Name |
NR5A1 Antibody - middle region (ARP31834_P050) |
| Protein Size (# AA) |
461 amino acids |
| Molecular Weight |
52kDa |
| NCBI Gene Id |
2516 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Nuclear receptor subfamily 5, group A, member 1 |
| Alias Symbols |
ELP, SF1, FTZ1, POF7, SF-1, AD4BP, FTZF1, SPGF8, SRXX4, SRXY3, hSF-1 |
| Peptide Sequence |
Synthetic peptide located within the following region: AVPGAHGPLAGYLYPAFPGRAIKSEYPEPYASPPQPGLPYGYPEPFSGGP |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Li,L.A., et al., (2004) J. Steroid Biochem. Mol. Biol. 91 (1-2), 11-20 |
| Description of Target |
NR5A1 is an important regulator of steroidogeneisis which is present in human skin and its appendages. It plays a role in regulating p450scc expression with TReP-132 and CBP/p300. The protein encoded by this gene is a transcriptional activator involved in sex determination. The encoded protein binds DNA as a monomer. Defects in this gene are a cause of XY sex reversal with or without adrenal failure as well as adrenocortical insufficiency without ovarian defect. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Protein Interactions |
NCK2; NR0B1; RAD54L2; THOC2; ALYREF; EIF4A3; DDX39B; UBC; BARD1; ELAVL1; TCF7L2; CTNNB1; CREBBP; CXXC1; PNRC2; SOX8; PIAS1; ZNF653; TRERF1; EDF1; GATA4; GTF2B; SOX2; SOX9; TBX19; NCOA1; NRIP1; PITX1; SMARCD3; PROX1; AR; SP1; NFYA; MAPK1; JUN; NFKB2; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-NR5A1 (ARP31834_P050) antibody |
| Blocking Peptide |
For anti-NR5A1 (ARP31834_P050) antibody is Catalog # AAP31834 (Previous Catalog # AAPP07402) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human NR5A1 |
| Uniprot ID |
Q13285 |
| Protein Name |
Steroidogenic factor 1 |
| Sample Type Confirmation |
NR5A1 is supported by BioGPS gene expression data to be expressed in HepG2 |
| Protein Accession # |
NP_004950 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_004959 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
NR5A1 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 92%; Dog: 92%; Guinea Pig: 92%; Horse: 92%; Human: 100%; Mouse: 79%; Rabbit: 85%; Rat: 92%; Sheep: 85% |
| Image 1 | Human Liver
 | Human Liver |
|
| Image 2 | Human kidney
 | Human kidney |
|
| Image 3 | Human Fetal Liver
 | Host: Rabbit
Target Name: NR5A1
Sample Type: Human Fetal Liver
Antibody Dilution: 1.0ug/ml |
|
| Image 4 | Human Fetal Heart
 | Host: Rabbit
Target Name: NR5A1
Sample Type: Human Fetal Heart
Antibody Dilution: 1.0ug/ml |
|
| Image 5 | Human Fetal Lung
 | Host: Rabbit
Target Name: NR5A1
Sample Type: Human Fetal Lung
Antibody Dilution: 1.0ug/ml |
|
| Image 6 | Human Fetal Liver
 | Host: Rabbit
Target Name: NR5A1
Sample Type: Human Fetal Liver
Antibody Dilution: 1.0ug/ml |
|
| Image 7 | Human Fetal Muscle
 | Host: Rabbit
Target Name: NR5A1
Sample Type: Human Fetal Muscle
Antibody Dilution: 1.0ug/ml |
|
| Image 8 | Human Adult Placenta
 | Host: Rabbit
Target Name: NR5A1
Sample Type: Human Adult Placenta
Antibody Dilution: 1.0ug/ml |
|
| Image 9 | Human HepG2
 | WB Suggested Anti-NR5A1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: HepG2 cell lysateNR5A1 is supported by BioGPS gene expression data to be expressed in HepG2 |
|
| Image 10 | Human heart
 | WB Suggested Anti-NR5A1 antibody Titration: 1 ug/mL
Sample Type: Human heart |
|
