ZNF384 Antibody - N-terminal region (OASG07652)

Catalog No: OASG07652

Size:100 uL

Western Blot using VEC

Product Info

• Predicted Species Reactivity: Human, Rat
• Product Format: Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: Store at -20C. Avoid repeated freeze/thaw cycles.
• Immunogen: Synthesized peptide derived from the N-terminal region of human ZNF384.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration: 1 mg/ml
• Specificity: ZNF384 Polyclonal Antibody detects endogenous levels of ZNF384 protein.
• Application Info: WB 1:500-1:2000; ELISA 1:20000;

Target Info

• Gene Symbol: ZFP384, ZNF384
• Gene Full Name: zinc finger protein 384
• Alias Symbols: NP, CIZ, NMP4, CAGH1, ERDA2, TNRC1, CAGH1A
• NCBI Gene Id: 171017; 171018
• Description of Target: This gene encodes a C2H2-type zinc finger protein, which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with the Ewing's sarcoma gene, EWSR1 on chromosome 22, or with the TAF15 gene on chromosome 17, or with the TCF3 (E2A) gene on chromosome 19, have been observed in acute leukemia. A related pseudogene has been identified on chromosome 7.
• Uniprot ID: Q8TF68, Q9EQJ4