Size:100 ul
$319.00
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ARP30976_P050
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Conjugation Options

ARP30976_P050-FITC Conjugated

ARP30976_P050-HRP Conjugated

ARP30976_P050-Biotin Conjugated

ZEB1 Antibody - N-terminal region (ARP30976_P050)

Rating:
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Catalog#: ARP30976_P050
Domestic: within 1-2 days delivery International: 1-2 days
More Information
Tested Species Reactivity Human
Predicted Species Reactivity Cow, Dog, Human, Mouse, Pig, Rabbit, Rat, Zebrafish
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Clonality Polyclonal
Host Rabbit
Application IHC, WB
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Replacement Item This antibody may replace item sc-10570 from Santa Cruz Biotechnology.
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human ZEB1
Purification Affinity Purified
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 100%; Rat: 93%; Zebrafish: 100%
Complete computational species homology data Anti-ZEB1 (ARP30976_P050)
Peptide Sequence Synthetic peptide located within the following region: NPRRNNVTNYNTVVETNSDSDDEDKLHIVEEESVTDAADCEGVPEDDLPT
Concentration Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking Peptide For anti-ZEB1 (ARP30976_P050) antibody is Catalog # AAPP34123
Datasheets/Manuals Printable datasheet for anti-ZEB1 (ARP30976_P050) antibody
Publications

Kothandaraman, N. et al. E2F5 status significantly improves malignancy diagnosis of epithelial ovarian cancer. BMC Cancer 10, 64 (2010). IHC, WB, Cow, Dog, Human, Mouse, Pig, Rabbit, Rat, Zebrafish 20181230

Li, J. et al. A strategy to rapidly identify the functional targets of microRNAs by combining bioinformatics and mRNA cytoplasmic/nucleic ratios in culture cells. FEBS Lett. 584, 3198-202 (2010). IHC, WB, Cow, Dog, Human, Mouse, Pig, Rabbit, Rat, Zebrafish 20547158

Gene Symbol ZEB1
Official Gene Full Name Zinc finger E-box binding homeobox 1
Alias Symbols AREB6, BZP, DELTA-EF1, FECD6, MGC133261, NIL-2-A, NIL-2A, NIL2A, TCF8, ZEB, ZFHEP, ZFHX1A, PPCD3, DELTAEF1
NCBI Gene Id 6935
Protein Name Zinc finger E-box-binding homeobox 1
Description of Target ZEB1 is a zinc finger transcription factor that represses T-lymphocyte-specific IL2 gene expression by binding to a negative regulatory domain 100 nucleotides 5-prime of the IL2 transcription start site.
Swissprot Id P37275
Protein Accession # NP_110378
Nucleotide Accession # NM_030751
Protein Size (# AA) 1124
Molecular Weight 124kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express ZEB1.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express ZEB1.
Protein Interactions SUMO1; CDK6; GTF2A1; UBR4; SUMO2; SIRT1; SOX2; CTBP2; CTBP1; SMAD7; SMAD6; SMARCA4; SERPINH1; SMAD3; EP300; DRAP1; KAT5; SMAD2; SMAD1; CDH1;
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