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- Phone: 858-552-6979
- Email: info@avivasysbio.com
- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
| Datasheets/Manuals | Printable datasheet for OAAF08362 |
|---|
| Tested Species Reactivity | Human |
|---|---|
| Product Format | Liquid. Supplied in 1% BSA, 0.05M Tris-HCl, 0.15M NaCl, 0.2% Kathon CG/ICP, 0.1% Tween-20 |
| Clonality | Monoclonal |
| Clone | ABT-ZAP70 |
| Isotype | IgG |
| Host | Mouse |
| Application | WB, IHC-P |
| Additional Information | Retrieval buffer: Citrate buffer of pH6.0 |
| :: | Description: Mouse monoclonal to ZAP-70 |
| Reconstitution and Storage | Shipped at 4C. Store at -20C. Stable for 12 months at -20C. |
| Immunogen | The antiserum was produced against synthesized peptide derived between 560-600 aa of human ZAP70. The exact sequence is proprietary. |
| Purification | Immunogen affinity purified |
| Specificity | Anti-ZAP-70 [ABT-ZAP70] detects endogenous levels of total ZAP-70 protein. |
| Application Info | IHC 1:200 - 1:400, WB 1:100 - 1:500 |
| Gene Symbol | ZAP70 |
|---|---|
| Gene Full Name | zeta chain of T cell receptor associated protein kinase 70 |
| Alias Symbols | SRK, STD, TZK, STCD, IMD48, ADMIO2, ZAP-70 |
| NCBI Gene Id | 7535 |
| Protein Name | tyrosine-protein kinase ZAP-70 |
| Description of Target | This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. |
| Uniprot ID | P43403 |
| Protein Accession # | NP_001070.2 |
| Nucleotide Accession # | NM_001079.3 |
| Molecular Weight | 70 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "ZAP70 Antibody (OAAF08362)"?
The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "".
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How long will it take to receive "ZAP70 Antibody (OAAF08362)"?
This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".
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What buffer format is "ZAP70 Antibody (OAAF08362)" provided in?
This item is provided in "Liquid. Supplied in 1% BSA, 0.05M Tris-HCl, 0.15M NaCl, 0.2% Kathon CG/ICP, 0.1% Tween-20".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "ZAP70 Antibody (OAAF08362)"?
This target may also be called "SRK, STD, TZK, STCD, IMD48, ADMIO2, ZAP-70" in publications.
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What is the shipping cost for "ZAP70 Antibody (OAAF08362)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "ZAP70 Antibody (OAAF08362)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "ZAP70 Antibody (OAAF08362)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "70 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "ZAP70 Antibody (OAAF08362)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "ZAP70"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "ZAP70"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "ZAP70"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "ZAP70"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "ZAP70"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "ZAP70"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
