YWHAH Protein (OPPA01702)

Catalog No: OPPA01702 (Formerly GWB-FCF804)

Size:5UG

Product Info

• Predicted Species Reactivity: Human
• Product Format: YWHAH solution containing 20mM Tris pH-8. Physical appearance: Sterile filtered colorless solution.
• Host: E. Coli
  Product Introduction: YWHAH belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. 14-3-3 ETA is found in plants and mammals, and there is 99% identity to the mouse, rat and bovine orthologs. YWHAH gene contains a 7 base pair repeat sequence in its 5' UTR, and changes in the number of this repeat has been associated with early-onset schizophrenia.14-3-3 eta is specific to the site of joint inflammation. 14-3-3 proteins are colocalized with Lewy bodies in Parkinson disease, though there is no specific staining for the 14-3-3 eta subunit. There are 3 different isoforms types of 14-3-3: Beta, Gamma and ETA that are DAL-1/Protein 4.1B-binding proteins.
  Product Description: YWHAH Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 266 amino acids and having a molecular mass of 30.3 kDa. YWHAH is fused to N-Terminus His Tag and purified by proprietary chromatographic techniques.
• Reconstitution and Storage: YWHAH Human Recombinant although stable at 4C for 1 week, should be stored desiccated below -18C. Please prevent freeze thaw cycles.
• Purity: Greater than 95.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
• Peptide Sequence: MGSSHHHHHH SSGLVPRGSH MGDREQLLQR ARLAEQAERY DMASAMKAV TELNEPLSNE DRNLLSVAYK NVVGARRSSW RVISSIEQKT MADGNEKKLE KVKAYREKIE KELETVCNDV LSLLDKFLIK NCNDFQYESK VFYLKMKGDY YRYLAEVASG EKKNSVVEAS EAAYKEAFEI SKEQMQPTHP IRLGLALNFS VFYYEIQNAP EQACLLAKQA FDDAIAELDT LNEDSYKDST LIMQLLRDNL TLWTSDQQDE EAGEGN.

Target Info

• Gene Symbol: YWHAH
• Alias Symbols: YWHA1
• NCBI Gene Id: 7533
• Protein Name: 14-3-3 protein eta
• Description of Target: Recombinant Human Tyr-3/Trp-5 Monooxygenase Activation Protein, ETA
• Uniprot ID: Q04917
• Protein Accession #: NP_003396.1
• Protein Size (# AA): Recombinant