Catalog No: AVARP02058_P050-HRP
Size:100ul
Price: $434.00
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AVARP02058_P050-HRP
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YWHAE Antibody - middle region : HRP (AVARP02058_P050-HRP)

Datasheets/ManualsPrintable datasheet for anti-YWHAE (AVARP02058_P050-HRP) antibody
Product Info
Predicted Species ReactivityMouse, Dog, Guinea Pig, Zebrafish
Product FormatLiquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
ClonalityPolyclonal
HostRabbit
ConjugationHRP: Horseradish Peroxidase
ApplicationWB
Reconstitution and StorageAll conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
ImmunogenThe immunogen is a synthetic peptide directed towards the middle region of human YWHAE
Predicted Homology Based on Immunogen SequenceDog: 100%; Guinea Pig: 100%; Mouse: 100%; Zebrafish: 100%
Peptide SequenceSynthetic peptide located within the following region: ELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQGDGEEQNKEALQDVEDEN
Concentration0.5 mg/ml
Blocking PeptideFor anti-YWHAE (AVARP02058_P050-HRP) antibody is Catalog # AAP30642 (Previous Catalog # AAPP01295)
ReferenceTak,H., (2007) Cell. Signal. 19 (11), 2379-2387
Gene SymbolYWHAE
Gene Full NameTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
Alias SymbolsMDS, HEL2, MDCR, KCIP-1, 14-3-3E
NCBI Gene Id7531
Protein Name14-3-3 protein epsilon
Description of TargetYWHAE is an adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. YWHAE binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. The binding generally results in the modulation of the activity of the binding partner.This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Uniprot IDP62258
Protein Accession #NP_006752
Nucleotide Accession #NM_006761
Protein Size (# AA)255
Molecular Weight29kDa
Protein InteractionsDTL; HUWE1; FAM53C; FBXW11; SORBS2; UBC; ABL1; GRB10; SIK2; CEP57; SIK3; TP53; IRS4; CBL; TUBB2A; TWF2; PROSC; FERMT2; PDIA4; RAP1GDS1; PTMA; PPP1R2; PDHB; PAK2; PAFAH1B2; YWHAH; XPO1; VCL; GSS; G6PD; EIF5; TBCB; CAPNS1; CAPN2; ALDH7A1; ATIC; ASNS; SCPEP1
  1. What is the species homology for "YWHAE Antibody - middle region : HRP (AVARP02058_P050-HRP)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Mouse, Dog, Guinea Pig, Zebrafish".

  2. How long will it take to receive "YWHAE Antibody - middle region : HRP (AVARP02058_P050-HRP)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "YWHAE Antibody - middle region : HRP (AVARP02058_P050-HRP)" provided in?

    This item is provided in "Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "YWHAE Antibody - middle region : HRP (AVARP02058_P050-HRP)"?

    This target may also be called "MDS, HEL2, MDCR, KCIP-1, 14-3-3E" in publications.

  5. What is the shipping cost for "YWHAE Antibody - middle region : HRP (AVARP02058_P050-HRP)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "YWHAE Antibody - middle region : HRP (AVARP02058_P050-HRP)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "YWHAE Antibody - middle region : HRP (AVARP02058_P050-HRP)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "29kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "YWHAE Antibody - middle region : HRP (AVARP02058_P050-HRP)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "YWHAE"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "YWHAE"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "YWHAE"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "YWHAE"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "YWHAE"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "YWHAE"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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