Aviva Systems Biology will be closed in observance of Good Friday 3/29/2024. If you are in need of any assistance please email info@avivasysbio.com

Catalog No: OACA09322
Price: $0.00
SKU
OACA09322
Bulk
Order
Aviva's
Satisfaction
Guarantee
Contact Us:
Shipping Info:
  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
  • Contact us for international orders.
Datasheets/ManualsPrintable datasheet for YME1L1 Antibody (OACA09322) (OACA09322)
Product Info
Predicted Species ReactivityHuman
Product FormatLiquid
ClonalityPolyclonal
IsotypeIgG
HostRabbit
ConjugationUnconjugated
ApplicationEnzyme-linked immunosorbent assay|Immunohistochemistry|Western blot
Reconstitution and Storage-20°C or -80°C
ImmunogenRecombinant Human ATP-dependent zinc metalloprotease YME1L1 protein (1-240AA)
PurificationAffinity Purified
Preservative0.02% sodium azide
FormulationPBS with, 50% glycerol, pH7.3.
Gene SymbolYME1L1
Gene Full NameYME1 like 1 ATPase
Alias SymbolsATP-dependent metalloprotease FtsH1;ATP-dependent metalloprotease FtsH1 homolog;ATP-dependent zinc metalloprotease YME1L1;FTSH;meg-4;MEG4;OPA11;PAMP;presenilin-associated metalloprotease;YME1L;YME1-like protein 1.
NCBI Gene Id10730
Protein NameATP-dependent zinc metalloprotease YME1L1
Description of TargetATP-dependent metalloprotease that catalyzes the degradation of folded and unfolded proteins with a suitable degron sequence in the mitochondrial intermembrane region (PubMed:26923599, PubMed:27786171). Plays an important role in regulating mitochondrial morphology and function by cleaving OPA1 at position S2, giving rise to a form of OPA1 that promotes maintenance of normal mitochondrial structure and mitochondrial protein metabolism (PubMed:18076378, PubMed:26923599, PubMed:27495975). Ensures cell proliferation, maintains normal cristae morphology and complex I respiration activity, promotes antiapoptotic activity and protects mitochondria from the accumulation of oxidatively damaged membrane proteins (PubMed:22262461). Required for normal, constitutive degradation of PRELID1 (PubMed:27495975). Catalyzes the degradation of OMA1 in response to membrane depolarization (PubMed:26923599). Required to control the accumulation of nonassembled respiratory chain subunits (NDUFB6, OX4 and ND1) (PubMed:22262461).
Uniprot IDQ96TA2
Protein Accession #NP_001240795
Nucleotide Accession #NM_001253866
  1. What is the species homology for "YME1L1 Antibody (OACA09322)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "YME1L1 Antibody (OACA09322)"?

    This item is available "Domestic: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks | International: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks".

  3. What buffer format is "YME1L1 Antibody (OACA09322)" provided in?

    This item is provided in "Liquid".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "YME1L1 Antibody (OACA09322)"?

    This target may also be called "ATP-dependent metalloprotease FtsH1;ATP-dependent metalloprotease FtsH1 homolog;ATP-dependent zinc metalloprotease YME1L1;FTSH;meg-4;MEG4;OPA11;PAMP;presenilin-associated metalloprotease;YME1L;YME1-like protein 1." in publications.

  5. What is the shipping cost for "YME1L1 Antibody (OACA09322)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "YME1L1 Antibody (OACA09322)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "YME1L1 Antibody (OACA09322)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "YME1L1 Antibody (OACA09322)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "YME1L1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "YME1L1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "YME1L1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "YME1L1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "YME1L1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "YME1L1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

Write Your Own Review
You're reviewing:YME1L1 Antibody (OACA09322)
Your Rating
We found other products you might like!