YAP1 Antibody - C-terminal region (ARP50530_P050)

Catalog No: ARP50530_P050

Host: Rabbit
Target Name: YAP1
Sample Tissue: Human Fetal Lung
Antibody Dilution: 1.0ug/ml

Host: Rabbit
Target: YAP1
Positive control (+): HepG2 (HG)
Negative control (-): Human heart (HE)
Antibody concentration: 1ug/ml

Immunohistochemistry with Human Prostate lysate tissue at an antibody concentration of 5.0ug/ml using anti-YAP1 antibody (ARP50530_P050)

Human Prostate

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Sheep, Zebrafish
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: IHC, WB
• Additional Information: IHC Information: Human Prostate (formalin-fixed, paraffin-embedded) stained with YAP1 antibody ARP50530_P050 followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.
  IHC Information: Human Prostate (formalin-fixed, paraffin-embedded) stained with YAP1 antibody ARP50530_P050 followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human YAP1
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 100%
• Peptide Sequence: Synthetic peptide located within the following region: QLPTLEQDGGTQNPVSSPGMSQELRTMTTNSSDPFLNSGTYHSRDESTDS
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-YAP1 (ARP50530_P050) antibody is Catalog # AAP50530 (Previous Catalog # AAPP13823)
• Publications:

  Allelic Expression Imbalance Analysis Identified YAP1 Amplification in p53- Dependent Osteosarcoma. Cancers (Basel). 13 (2021). 33803512

• Description:
  View product citations for YAP1 Antibody - C-terminal region (ARP50530_P050) on CiteAb

Target Info

• Gene Symbol: YAP1
• Gene Full Name: Yes-associated protein 1
• Alias Symbols: YAP, YKI, COB1, YAP2, YAP65
• NCBI Gene Id: 10413
• Protein Name: Yorkie homolog
• Description of Target: YAP1 is the human ortholog of chicken YAP protein which binds to the SH3 domain of the Yes proto-oncogene product. YAP1 contains a WW domain that is found in various structural, regulatory and signaling molecules in yeast, nematode, and mammals, and may be involved in protein-protein interaction.
• Uniprot ID: P46937
• Protein Accession #: NP_001123617
• Nucleotide Accession #: NM_001130145
• Protein Size (# AA): 504
• Molecular Weight: 54kDa
• Protein Interactions: ABL1; TP73; RUNX1; AMOT; UBC; FBXW7; ARFIP1; RTF1; PAPOLA; PRMT3; TOM1; TSNAX; STAT1; MAP2K1; NF2; WBP2; RASSF8; YWHAQ; INADL; RAPGEF2; TJP2; SLC9A3R2; PDLIM7; LATS1; MPDZ; RAE1; ARID1A; YWHAZ; YWHAH; YWHAG; YWHAE; YWHAB; TP53BP2; TEAD3; TEAD1; SMARCD1; D