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Catalog No: ARP31459_T100-Biotin
Size:100ul
Price: $384.00
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ARP31459_T100-Biotin
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YAF2 Antibody - middle region : Biotin (ARP31459_T100-Biotin)

Datasheets/ManualsPrintable datasheet for anti-YAF2 (ARP31459_T100-Biotin) antibody
Product Info
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer.
ClonalityPolyclonal
HostRabbit
ConjugationBiotin
ApplicationIHC, WB
Reconstitution and StorageAll conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
ImmunogenThe immunogen is a synthetic peptide directed towards the middle region of human YAF2
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 86%; Rabbit: 100%; Rat: 100%
Peptide SequenceSynthetic peptide located within the following region: KGTSTRKPRPVSQLVAQQVTQQFVPPTQSKKEKKDKVEKEKSEKETTSKK
Concentration0.5 mg/ml
Blocking PeptideFor anti-YAF2 (ARP31459_T100-Biotin) antibody is Catalog # AAP31459 (Previous Catalog # AAPP24060)
ReferenceMadge,B., (2003) Cancer Lett. 193 (2), 171-176
Gene SymbolYAF2
Gene Full NameYY1 associated factor 2
Alias SymbolsMGC41856
NCBI Gene Id10138
Protein NameYY1-associated factor 2
Description of TargetYAF2 interacts with YY1, a zinc finger protein involved in negative regulation of muscle-restricted genes. YAF2 contains a single N-terminal C2-X10-C2 zinc finger, and in contrast to YY1, is up-regulated during myogenic differentiation. It also facilitates proteolytic cleavage of YY1 by the calcium- activated protease, m-calpain, suggesting a mechanism by which this protein antagonizes the negative effect of YY1.The protein encoded by this gene interacts with YY1, a zinc finger protein involved in negative regulation of muscle-restricted genes. This gene product itself contains a single N-terminal C2-X10-C2 zinc finger, and in contrast to YY1, is up-regulated during myogenic differentiation. It also facilitates proteolytic cleavage of YY1 by the calcium- activated protease, m-calpain, suggesting a mechanism by which this protein antagonizes the negative effect of YY1. Multiple transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two have been confirmed to date.
Uniprot IDQ8IY57
Protein Accession #NP_005739
Nucleotide Accession #NM_005748
Protein Size (# AA)180
Molecular Weight20kDa
Protein InteractionsSETBP1; XAGE1E; RING1; RNF2; BMI1; GABPB1; CSNK2A2; UBC; CAND1; PCGF1; KDM2B; PCGF5; PCGF6; L3MBTL2; FBRS; BCORL1; BCOR; MGA; CBX3; WDR5; PCGF3; YAF2; USP7; PCGF2; TFDP1; SKP1; HDAC2; E2F6; CSNK2A1; ZFP42; YY1; MYCN;
  1. What is the species homology for "YAF2 Antibody - middle region : Biotin (ARP31459_T100-Biotin)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit".

  2. How long will it take to receive "YAF2 Antibody - middle region : Biotin (ARP31459_T100-Biotin)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "YAF2 Antibody - middle region : Biotin (ARP31459_T100-Biotin)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "YAF2 Antibody - middle region : Biotin (ARP31459_T100-Biotin)"?

    This target may also be called "MGC41856" in publications.

  5. What is the shipping cost for "YAF2 Antibody - middle region : Biotin (ARP31459_T100-Biotin)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "YAF2 Antibody - middle region : Biotin (ARP31459_T100-Biotin)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "YAF2 Antibody - middle region : Biotin (ARP31459_T100-Biotin)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "20kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "YAF2 Antibody - middle region : Biotin (ARP31459_T100-Biotin)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "YAF2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "YAF2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "YAF2"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "YAF2"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "YAF2"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "YAF2"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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