Catalog No: ARP49703_P050
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ARP49703_P050
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Datasheets/ManualsPrintable datasheet for anti-XYLT2 (ARP49703_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the C terminal region of human XYLT2
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Complete computational species homology dataAnti-XYLT2 (ARP49703_P050)
Peptide SequenceSynthetic peptide located within the following region: LRPGPWTVRLLQFWEPLGETRFLVLPLTFNRKLPLRKDDASWLHAGPPHN
Concentration0.5 mg/ml
Blocking PeptideFor anti-XYLT2 (ARP49703_P050) antibody is Catalog # AAP49703 (Previous Catalog # AAPP29284)
ReferenceCasanova,J.C., (2008) Biochem. Biophys. Res. Commun. 365 (4), 678-684
Gene SymbolXYLT2
Gene Full NameXylosyltransferase II
Alias SymbolsSOS, XT2, XT-II, PXYLT2, xylT-II
NCBI Gene Id64132
Protein NameXylosyltransferase 2
Description of TargetXYLT2 is an isoform of xylosyltransferase, which belongs to a family of glycosyltransferases. This enzyme transfers xylose from UDP-xylose to specific serine residues of the core protein and initiates the biosynthesis of glycosaminoglycan chains in proteoglycans including chondroitin sulfate, heparan sulfate, heparin and dermatan sulfate. The enzyme activity, which is increased in scleroderma patients, is a diagnostic marker for the determination of sclerotic activity in systemic sclerosis.The protein encoded by this gene is an isoform of xylosyltransferase, which belongs to a family of glycosyltransferases. This enzyme transfers xylose from UDP-xylose to specific serine residues of the core protein and initiates the biosynthesis of glycosaminoglycan chains in proteoglycans including chondroitin sulfate, heparan sulfate, heparin and dermatan sulfate. The enzyme activity, which is increased in scleroderma patients, is a diagnostic marker for the determination of sclerotic activity in systemic sclerosis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Swissprot IdQ9H1B5
Protein Accession #NP_071450
Nucleotide Accession #NM_022167
Protein Size (# AA)865
Molecular Weight97 kDa
Tissue ToolFind tissues and cell lines supported by DNA array analysis to express XYLT2.
RNA SeqFind tissues and cell lines supported by RNA-seq analysis to express XYLT2.
  1. What is the species homology for "XYLT2 Antibody - C-terminal region (ARP49703_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit".

  2. How long will it take to receive "XYLT2 Antibody - C-terminal region (ARP49703_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "XYLT2 Antibody - C-terminal region (ARP49703_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "XYLT2 Antibody - C-terminal region (ARP49703_P050)"?

    This target may also be called "SOS, XT2, XT-II, PXYLT2, xylT-II" in publications.

  5. What is the shipping cost for "XYLT2 Antibody - C-terminal region (ARP49703_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "XYLT2 Antibody - C-terminal region (ARP49703_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "XYLT2 Antibody - C-terminal region (ARP49703_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "97 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "XYLT2 Antibody - C-terminal region (ARP49703_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "XYLT2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "XYLT2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "XYLT2"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "XYLT2"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "XYLT2"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "XYLT2"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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