XRN1 Recombinant Protein (OPCD00144)

Catalog No: OPCD00144

XRN1 Recombinant Protein (OPCD00144) using SDS-PAGE

XRN1 Recombinant Protein (OPCD00144) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Tyr1394-Glu1706
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: XRN1
• Gene Full Name: 5'-3' exoribonuclease 1
• Alias Symbols: 5'-3' exoribonuclease 1;SEP1;strand-exchange protein 1 homolog.
• NCBI Gene Id: 54464
• Protein Name: 5'-3' exoribonuclease 1
• Description of Target: Major 5'-3' exoribonuclease involved in mRNA decay. Required for the 5'-3'-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA (By similarity). Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma (OGS).
• Uniprot ID: Q8IZH2
• Protein Accession #: NP_001269786.1
• Nucleotide Accession #: NM_001282857.1
• Protein Size (# AA): Tyr1394~Glu1706
• Molecular Weight: 37kDa