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XPOT antibody - middle region (ARP40711_P050)

100 ul
$319.00
In Stock

Conjugation Options

ARP40711_P050-FITC Conjugated

ARP40711_P050-HRP Conjugated

ARP40711_P050-Biotin Conjugated

Gene Symbol:
XPOT
NCBI Gene Id:
11260
Official Gene Full Name:
Exportin, tRNA (nuclear export receptor for tRNAs)
Protein Name:
Exportin-T
Swissprot Id:
O43592
Protein Accession #:
NP_009166
Nucleotide Accession #:
NM_007235
Alias Symbols:
XPO3
Replacement Item:
This antibody may replace item sc-136346 from Santa Cruz Biotechnology.
Description of Target:
XPOT belonging to the RAN-GTPase exportin family that mediates export of tRNA from the nucleus to the cytoplasm. Translocation of tRNA to the cytoplasm occurs once exportin has bound both tRNA and GTP-bound RAN.This gene encodes a protein belonging to the RAN-GTPase exportin family that mediates export of tRNA from the nucleus to the cytoplasm. Translocation of tRNA to the cytoplasm occurs once exportin has bound both tRNA and GTP-bound RAN.
Protein Size (# AA):
962
Molecular Weight:
110kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
IHC, WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express XPOT.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express XPOT.
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of human XPOT
Species Reactivity:
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish
Predicted Homology Based on Immunogen Sequence:
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 75%; Zebrafish: 93%
Complete computational species homology data:
Anti-XPOT (ARP40711_P050)
Peptide Sequence:
Synthetic peptide located within the following region: TVLSDQQKANVEAIMLAVMKKLTYDEEYNFENEGEDEAMFVEYRKQLKLL
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
SUMO2; SUMO3; UBC; RNF2; MCMBP; PAPSS1; NFRKB; APEX1; FBXO6; EGFR; IQCB1; CA9; ECT2; TXNL1; USP7; UBD; RAN; CUL5; FBXO25; SIRT7; EBNA-LP; HDAC5; MYC; CAMKK2; CLN3; AIRE; XPO7; NUP153; RANBP2; HDLBP; NUP214;
Blocking Peptide:
For anti-XPOT (ARP40711_P050) antibody is Catalog # AAP40711 (Previous Catalog # AAPY00963)
Datasheets/Manuals:
Printable datasheet for anti-XPOT (ARP40711_P050) antibody
Sample Type Confirmation:

XPOT is supported by BioGPS gene expression data to be expressed in Jurkat

Target Reference:
Li,S. (2006) RNA Biol 3 (4), 145-149

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