Catalog No: OACA10444
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OACA10444
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  • $55: Antibody & Protein in US
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Datasheets/ManualsPrintable datasheet for XPO1 Antibody (OACA10444) (OACA10444)
Product Info
Predicted Species ReactivityHuman|Mouse
Product FormatLiquid
ClonalityPolyclonal
IsotypeIgG
HostRabbit
ConjugationUnconjugated
ApplicationEnzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Western blot
Reconstitution and Storage-20°C or -80°C
ImmunogenRecombinant Human Exportin-1 protein (625-845AA)
PurificationProtein G Purified
Preservative0.03% Proclin 300
Formulation50% Glycerol, 0.01M PBS, pH 7.4
Purity>95%
Gene SymbolXPO1
Gene Full Nameexportin 1
Alias Symbolschromosome region maintenance 1 homolog;chromosome region maintenance 1 protein homolog;CRM1;CRM-1;emb;exp1;exportin 1 (CRM1 homolog, yeast);exportin-1;exportin-1 (required for chromosome region maintenance).
NCBI Gene Id7514
Protein NameExportin-1
Description of TargetMediates the nuclear export of cellular proteins (cargos) bearing a leucine-rich nuclear export signal (NES) and of RNAs. In the nucleus, in association with RANBP3, binds cooperatively to the NES on its target protein and to the GTPase RAN in its active GTP-bound form (Ran-GTP). Docking of this complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the cargo from the export receptor. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. Involved in U3 snoRNA transport from Cajal bodies to nucleoli. Binds to late precursor U3 snoRNA bearing a TMG cap. Several viruses, among them HIV-1, HTLV-1 and influenza A use it to export their unspliced or incompletely spliced RNAs out of the nucleus. Interacts with, and mediates the nuclear export of HIV-1 Rev and HTLV-1 Rex proteins. Involved in HTLV-1 Rex multimerization.
Uniprot IDO14980
Protein Accession #NP_003391
Nucleotide Accession #NM_003400
  1. What is the species homology for "XPO1 Antibody (OACA10444)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse".

  2. How long will it take to receive "XPO1 Antibody (OACA10444)"?

    This item is available "Domestic: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks | International: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks".

  3. What buffer format is "XPO1 Antibody (OACA10444)" provided in?

    This item is provided in "Liquid".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "XPO1 Antibody (OACA10444)"?

    This target may also be called "chromosome region maintenance 1 homolog;chromosome region maintenance 1 protein homolog;CRM1;CRM-1;emb;exp1;exportin 1 (CRM1 homolog, yeast);exportin-1;exportin-1 (required for chromosome region maintenance)." in publications.

  5. What is the shipping cost for "XPO1 Antibody (OACA10444)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "XPO1 Antibody (OACA10444)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "XPO1 Antibody (OACA10444)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "XPO1 Antibody (OACA10444)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "XPO1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "XPO1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "XPO1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "XPO1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "XPO1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "XPO1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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