XPO1 Antibody - N-terminal region (OAGA04555)

Catalog No: OAGA04555

Size:100 ul

Sample (30 ug of whole cell lysate)
A: HeLa
5% SDS PAGE
diluted at 1:500
The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.

Immunohistochemical analysis of paraffin-embedded human colon carcinoma, using CRM1 antibody at 1:250 dilution.

Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using CRM1 antibody at 1:500 dilution.

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: ICC, IF, IHC-P, WB
• Reconstitution and Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human CRM1. The exact sequence is proprietary.
• Purification: Purified by antigen-affinity chromatography.
• Concentration: 1 mg/ml
• Preservative: 0.01% Thimerosal
• Application Info: Suggested starting dilutions are as follows: ICC/IF: 1:100-1:1000, IHC-P: 1:100-1:1000, WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
• Storage Buffer: 1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Target Info

• Gene Symbol: XPO1
• Gene Full Name: exportin 1
• Alias Symbols: emb, CRM1, exp1, CRM-1
• NCBI Gene Id: 7514
• Protein Name: exportin-1
• Description of Target: This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1.
• Uniprot ID: O14980
• Protein Accession #: NP_003391.1
• Nucleotide Accession #: NM_003400.3