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Now Offering Over 102,157 Antibodies & 44,722 Antigens!

XPO1 antibody - C-terminal region (ARP40465_P050)

100 ul
$319.00
In Stock

Conjugation Options

ARP40465_P050-FITC Conjugated

ARP40465_P050-HRP Conjugated

ARP40465_P050-Biotin Conjugated

Gene Symbol:
XPO1
NCBI Gene Id:
7514
Official Gene Full Name:
Exportin 1 (CRM1 homolog, yeast)
Protein Name:
Exportin-1
Swissprot Id:
O14980
Protein Accession #:
NP_003391
Nucleotide Accession #:
NM_003400
Alias Symbols:
CRM1, DKFZp686B1823, emb, exp1
Replacement Item:
This antibody may replace item sc-373865 from Santa Cruz Biotechnology.
Description of Target:
XPO1 mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. XPO1 also regulates NFAT and AP-1.The protein encoded by this gene mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Protein Size (# AA):
1071
Molecular Weight:
123kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
IHC, WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express XPO1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express XPO1.
Immunogen:
The immunogen is a synthetic peptide directed towards the C terminal region of human XPO1
Species Reactivity:
Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat, Yeast, Zebrafish
Predicted Homology Based on Immunogen Sequence:
Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Yeast: 85%; Zebrafish: 93%
Complete computational species homology data:
Anti-XPO1 (ARP40465_P050)
Peptide Sequence:
Synthetic peptide located within the following region: NKLGGHITAEIPQIFDAVFECTLNMINKDFEEYPEHRTNFFLLLQAVNSH
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
ABL1; UBC; HUWE1; ELAVL1; KEAP1; SUMO2; SUMO3; USP16; STAU1; CDC37L1; RNF2; rev; TUBB; SCPEP1; CAMK1D; DCPS; HSPA1L; HNRNPK; GNAI3; EEF2; CAPN2; TWF2; FERMT2; UBA3; NAE1; STK24; YWHAH; YWHAE; VCL; TUFM; PCYT2; PPP5C; PPP1CA; EGFR; LOC366310; CLN5; CLN3; S
Blocking Peptide:
For anti-XPO1 (ARP40465_P050) antibody is Catalog # AAP40465 (Previous Catalog # AAPP22233)
Datasheets/Manuals:
Printable datasheet for anti-XPO1 (ARP40465_P050) antibody
Sample Type Confirmation:

XPO1 is supported by BioGPS gene expression data to be expressed in HeLa, HepG2

Target Reference:
Cheong,J.K., (2008) J. Biol. Chem. 283 (17), 11661-11676

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