WWP2 Antibody - middle region : FITC (ARP43088_P050-FITC)

Catalog No: ARP43088_P050-FITC

Size:100ul

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer.
• Clonality: Polyclonal
• Host: Rabbit
• Conjugation: FITC: Fluorescein Isothiocyanate
• Application: IHC, WB
• Reconstitution and Storage: All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human WWP2
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 93%; Sheep: 100%; Zebrafish: 80%
• Peptide Sequence: Synthetic peptide located within the following region: EMKYTSEGVRYFVDHNTRTTTFKDPRPGFESGTKQGSPGAYDRSFRWKYH
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-WWP2 (ARP43088_P050-FITC) antibody is Catalog # AAP43088 (Previous Catalog # AAPP25063)
• Sample Type Confirmation:

  WWP2 is supported by BioGPS gene expression data to be expressed in Jurkat

• Reference: Rougier,J.S., Am. J. Physiol., Cell Physiol. 288 (3), C692-C701 (2005)

Target Info

• Gene Symbol: WWP2
• Gene Full Name: WW domain containing E3 ubiquitin protein ligase 2
• Alias Symbols: AIP2, WWp2-like
• NCBI Gene Id: 11060
• Protein Name: NEDD4-like E3 ubiquitin-protein ligase WWP2
• Description of Target: WWP2 is a member of the NEDD4-like protein family. The family of proteins is known to possess ubiquitin-protein ligase activity. WWP2 contains 4 tandem WW domains. The WW domain is a protein motif consisting of 35 to 40 amino acids and is characterized by 4 conserved aromatic residues. The WW domain may mediate specific protein-protein interactions.This gene encodes a member of the NEDD4-like protein family. The family of proteins is known to possess ubiquitin-protein ligase activity. The encoded protein contains 4 tandem WW domains. The WW domain is a protein motif consisting of 35 to 40 amino acids and is characterized by 4 conserved aromatic residues. The WW domain may mediate specific protein-protein interactions. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
• Uniprot ID: O00308
• Protein Accession #: NP_955456
• Nucleotide Accession #: NM_199424
• Protein Size (# AA): 431
• Molecular Weight: 47kDa
• Protein Interactions: LGALS9B; ANKRD44; FBXL18; VPS37C; PABPC1; RUSC1; HNRNPUL1; WWP2; PAIP1; TRAF4; FAM189A2; PDLIM7; EIF3A; WIPF1; UBE2L3; UBC; SNRPC; PTCH1; SMAD6; SMAD3; EZH2; PTEN; UBE2D3; FBXL15; RNF11; ARRDC1; ARRDC4; ARRDC3; VPS11; UBE2G1; UBE2J2; UBE2E3; UBE2E1; UBE2D