WWP1 Antibody (OAGA03668)

Catalog No: OAGA03668

Size:100 ul

WWP1 antibody detects WWP1 protein at cytosol on mouse stomach by immunohistochemical analysis.
Sample: Paraffin-embedded mouse stomach.
WWP1 antibody dilution: 1:500.

WWP1 antibody detects WWP1 protein at cytoplasm in mouse liver by immunohistochemical analysis.
Sample: Paraffin-embedded mouse liver.
WWP1 antibody diluted at 1:500.

Product Info

• Predicted Species Reactivity: Mouse
• Product Format: Liquid
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: IHC-P
• Reconstitution and Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Immunogen: Recombinant protein encompassing a sequence within the center region of human WWP1. The exact sequence is proprietary.
• Purification: Purified by antigen-affinity chromatography.
• Concentration: 1 mg/ml
• Preservative: 0.01% Thimerosal
• Application Info: Suggested starting dilutions are as follows: IHC-P: 1:100-1:1000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
• Storage Buffer: 1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Target Info

• Gene Symbol: WWP1
• Gene Full Name: WW domain containing E3 ubiquitin protein ligase 1
• Alias Symbols: AIP5, Tiul1, hSDRP1
• NCBI Gene Id: 11059
• Protein Name: NEDD4-like E3 ubiquitin-protein ligase WWP1
• Description of Target: WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 4 tandem WW domains and a HECT (homologous to the E6-associated protein carboxyl terminus) domain. The encoded protein belongs to a family of NEDD4-like proteins, which are E3 ubiquitin-ligase molecules and regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes. Alternative splicing of this gene generates at least 6 transcript variants; however, the full length nature of these transcripts has not been defined.
• Uniprot ID: Q9H0M0
• Protein Accession #: NP_008944.1
• Nucleotide Accession #: NM_007013.3