Product Protocols: GTF2A1L antibody tested with Human Hepg2 Cells (ARP50819_P050)

Aviva Systems Biology is the original manufacturer of this GTF2A1L antibody (ARP50819_P050)

Click here to view the GTF2A1L antibody Western Blot Protocol

Product Datasheet Link: GTF2A1L antibody (ARP50819_P050)

WB Suggested Anti-GTF2A1L Antibody Titration: 0.2-1 ug/ml
Positive Control: HepG2

Western Blot image:

Description of Target: The assembly and stability of the RNA polymerase II transcription pre-initiation complex on a eukaryotic core promoter involve the effects of TFIIA on the interaction between TATA-binding protein (TBP) and DNA. This gene encodes a germ cell-specific counterpart of the large (alpha/beta) subunit of general transcription factor TFIIA that is able to stabilize the binding of TBP to DNA and may be uniquely important to testis biology.The assembly and stability of the RNA polymerase II transcription pre-initiation complex on a eukaryotic core promoter involve the effects of TFIIA on the interaction between TATA-binding protein (TBP) and DNA. This gene encodes a germ cell-specific counterpart of the large (alpha/beta) subunit of general transcription factor TFIIA that is able to stabilize the binding of TBP to DNA and may be uniquely important to testis biology. Alternative splicing for this locus has been observed and two variants, encoding distinct isoforms, have been identified. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (SALF), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.

Questions pertaining to this data can be directed to techsupport@avivasysbio.com

Aviva Systems Biology’s GTF2A1L antibody (ARP50819_P050) has been tested using other cell lysates and tissues. To obtain more data about this antibody please email us at info@avivasysbio.com.

To order by phone call us at (888) 880-0001, fax us at (858) 552-6975 or send an email to info@avivasysbio.com. Aviva manufactures this antibody so we can offer the best price. Please contact us to request pricing information.

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