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Catalog No: OPCD07973 (Formerly GWB-FX5MDO)
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OPCD07973
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WNT3A Recombinant Protein (OPCD07973)

Datasheets/ManualsPrintable datasheet for WNT3A Recombinant Protein (OPCD07973)
Product Info
Predicted Species ReactivityHomo sapiens|Human
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
HostE.coli
ConjugationUnconjugated
ApplicationPositive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
Subcellular Location: Secreted, extracellular matrix.
Isoelectric Point: 8.6
::Residues: Ser19-Lys352
Reconstitution and Storage2°C to 8°C|-80°C
Concentration200 ug/mL (prior to lyoph)
Purity> 97%
SourceE.coli
TagN-terminal His Tag
Gene SymbolWNT3A
Gene Full NameWnt family member 3A
Alias Symbolsprotein Wnt-3a;wingless-type MMTV integration site family, member 3A.
NCBI Gene Id89780
Protein NameProtein Wnt-3a
Description of TargetLigand for members of the frizzled family of seven transmembrane receptors (Probable). Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (PubMed:20093360, PubMed:21244856, PubMed:24841207, PubMed:26902720). Required for normal embryonic mesoderm development and formation of caudal somites. Required for normal morphogenesis of the developing neural tube (By similarity). Mediates self-renewal of the stem cells at the bottom on intestinal crypts (in vitro) (PubMed:26902720).
Uniprot IDP56704
Protein Accession #NP_149122.1
Nucleotide Accession #NM_033131.3
Protein Size (# AA)Met1~Phe290
Molecular Weight41kDa
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