Wnt10a Antibody (OAPB00695)

Catalog No: OAPB00695

Size:100UG

Western blot analysis of Wnt10a in RAW264.7 cell lysate with Wnt10a antibody at (A) 1 and (B) 2 ug/mL.

Immunohistochemistry of Wnt10a in human skeletal muscle tissue cells with Wnt10a antibody at 10 ug/mL.

Product Info

• Predicted Species Reactivity: Human|Mouse|Rat
• Product Format: Liquid. Wnt10a Antibody is supplied in PBS containing 0.02% sodium azide.
• Clonality: Polyclonal
• Host: Rabbit
• Conjugation: Unconjugated
• Application: Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot
  Buffer: Antibody is supplied in PBS containing 0.02% sodium azide.
• Reconstitution and Storage: Wnt10a antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Immunogen: Wnt10a antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human Wnt10a. The immunogen is located within amino acids 300 - 350 of Wnt10a.
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Human; Mouse; Rat
• Concentration: 1 mg/ml
• Blocking Peptide: For anti-Wnt10a antibody is Catalog # OEPB02811
• Application Info: Wnt10a antibody can be used for detection of Wnt10a by Western blot at 1 - 2 ug/ml. (Optimal dilution should be determined by user)
• Reference: Kelly GM, Lai CJ, and Moon RT. Expression of wnt10a in the central nervous system of developing zebrafish. Dev. Biol.1993; 158:113-21.;Nusse R and Varmus RE. Wnt genes. Cell1992; 69:1073-87.;Kirikoshi H, Sekihara H, and Katoh M. WNT10A and WNT6, clustered in human chromosome 2q35 region head-to-tail manner, are strongly coexpressed in SW480 cells. Biochem. Biophys. Res. Commun.2001; 283:798-805.;Kirikoshi H, Inoue S, Sekihara H, et al. Expression of WNT10A in human cancer. Int. J. Oncol.2001; 19:997-1001.

Target Info

• Gene Symbol: WNT10A
• Gene Full Name: Wnt family member 10A
• Alias Symbols: OODD;protein Wnt-10a;SSPS;STHAG4;wingless-type MMTV integration site family, member 10A.
• NCBI Gene Id: 80326
• Protein Name: Protein Wnt-10a
• Description of Target: Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Functions in the canonical Wnt/beta-catenin signaling pathway (By similarity). Plays a role in normal ectoderm development (PubMed:17847007, PubMed:28589954). Required for normal tooth development (PubMed:17847007, PubMed:29178643, PubMed:28589954). Required for normal postnatal development and maintenance of tongue papillae and sweat ducts (PubMed:28589954). Required for normal proliferation of basal cells in tongue filiform papillae, plantar epithelium and sweat ducts. Required for normal expression of keratins in tongue papillae (By similarity). Required for normal expression of KRT9 in foot plant epithelium (PubMed:28589954). Required for normal hair follicle function (PubMed:28589954).
• Uniprot ID: Q9GZT5
• Molecular Weight: Predicted: 46 kDa Observed: 46 kDa