- Toll Free: 888-880-0001
- Phone: 858-552-6979
- Email: info@avivasysbio.com
- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
| Datasheets/Manuals | Printable datasheet for WIPI1 Antibody - C-terminal (OAPB01650) (OAPB01650) |
|---|
| Predicted Species Reactivity | Human|Mouse|Rat |
|---|---|
| Product Format | Liquid. WIPI1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Host | Rabbit |
| Conjugation | Unconjugated |
| Application | Enzyme-linked immunosorbent assay|Immunofluorescence|Western blot |
| Reconstitution and Storage | For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Immunogen | WIPI1 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human WIPI1. The immunogen is located within amino acids 350 - 400 of WIPI1. |
| Purification | Affinity Purified |
| Concentration | 1 mg/ml |
| Gene Symbol | WIPI1 |
|---|---|
| Gene Full Name | WD repeat domain, phosphoinositide interacting 1 |
| Alias Symbols | ATG18;atg18 protein homolog;ATG18A;WD repeat domain phosphoinositide-interacting protein 1;WD40 repeat protein interacting with phosphoinositides of 49 kDa;WIPI-1 alpha;WIPI49. |
| NCBI Gene Id | 55062 |
| Protein Name | WD repeat domain phosphoinositide-interacting protein 1|WD repeat domain phosphoinositide-interacting protein 1 isoform a [Homo sapiens] |
| Description of Target | Plays an important role in autophagy and in particular starvation- and calcium-mediated autophagy, as well as in mitophagy. Functions upstream of the ATG12-ATG5-ATG16L1 complex and LC3, and downstream of the ULK1 and PI3-kinase complexes. Involved in xenophagy of Staphylococcus aureus. Invading S.aureus cells become entrapped in autophagosome-like WIPI1 positive vesicles targeted for lysosomal degradation. Plays also a distinct role in controlling the transcription of melanogenic enzymes and melanosome maturation, a process that is distinct from starvation-induced autophagy. May also regulate the trafficking of proteins involved in the mannose-6-phosphate receptor (MPR) recycling pathway. |
| Uniprot ID | Q5MNZ9 |
| Protein Accession # | https://www.ncbi.nlm.nih.gov/protein/NP_060453 |
| Nucleotide Accession # | NM_001320772.1 |
| Molecular Weight | 49 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
-
See our General FAQ page.
-
What is the species homology for "WIPI1 Antibody - C-terminal (OAPB01650)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse|Rat".
-
How long will it take to receive "WIPI1 Antibody - C-terminal (OAPB01650)"?
This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".
-
What buffer format is "WIPI1 Antibody - C-terminal (OAPB01650)" provided in?
This item is provided in "Liquid. WIPI1 Antibody is supplied in PBS containing 0.02% sodium azide.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "WIPI1 Antibody - C-terminal (OAPB01650)"?
This target may also be called "ATG18;atg18 protein homolog;ATG18A;WD repeat domain phosphoinositide-interacting protein 1;WD40 repeat protein interacting with phosphoinositides of 49 kDa;WIPI-1 alpha;WIPI49." in publications.
-
What is the shipping cost for "WIPI1 Antibody - C-terminal (OAPB01650)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
-
What is the guarantee for "WIPI1 Antibody - C-terminal (OAPB01650)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
-
Can I get bulk pricing for "WIPI1 Antibody - C-terminal (OAPB01650)"?
You can get bulk pricing for this item by going here.
-
What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "49 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "WIPI1 Antibody - C-terminal (OAPB01650)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
-
What are positive controls for "WIPI1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
-
What are negative controls for "WIPI1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
-
What other proteins interact with "WIPI1"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
-
What biological processes are associated with "WIPI1"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
-
What cellular components are associated with "WIPI1"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
-
What protein functions are associated with "WIPI1"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
