WAPL Antibody - middle region : FITC (ARP75435_P050-FITC)

Catalog No: ARP75435_P050-FITC

Size:100ul

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Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer.
• Clonality: Polyclonal
• Host: Rabbit
• Conjugation: FITC: Fluorescein Isothiocyanate
• Application: WB
• Reconstitution and Storage: All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human WAPL
• Purification: Affinity purified
• Peptide Sequence: Synthetic peptide located within the following region: KSKKDVKLEFFGFEDHETGGDEGGSGSSNYKIKYFGFDDLSESEDDEDDD
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-WAPL (ARP75435_P050-FITC) antibody is Catalog # AAP75435
• Reference: N/A

Target Info

• Gene Symbol: WAPL
• Alias Symbols: FOE, WAPAL, KIAA0261
• NCBI Gene Id: 23063
• Description of Target: WAPL is a regulator of sister chromatid cohesion in mitosis which negatively regulates cohesin association with chromatin. It is involved in both sister chromatid cohesion during interphase and sister- chromatid resolution during early stages of mitosis. It couples DNA replication to sister chromatid cohesion. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair.
• Uniprot ID: Q7Z5K2
• Protein Accession #: NP_055860
• Protein Size (# AA): 1190
• Molecular Weight: 130kDa
• Protein Interactions: UBC; RPA3; RPA2; RPA1; XRN1; PDS5A; SMC3; VCP; VPS16; WRAP53; USP15; USP10; NSMCE2; ELAVL1; SUMO2; RAD21; ARAP1; Stag2; WAPAL; PDS5B; STAG1; SMC1A; SRRM1;