VPS4B Antibody - N-terminal region (ARP61680_P050)

Catalog No: ARP61680_P050

WB Suggested Anti-VPS4B Antibody
Titration: 1.0 ug/ml
Positive Control: OVCAR-3 Whole CellVPS4B is supported by BioGPS gene expression data to be expressed in OVCAR3

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Rabbit: 86%; Rat: 100%
• Peptide Sequence: Synthetic peptide located within the following region: EKLKEYLKNKEKKAQKPVKEGQPSPADEKGNDSDGEGESDDPEKKKLQNQ
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-VPS4B (ARP61680_P050) antibody is Catalog # AAP61680 (Previous Catalog # AAPP47774)
• Sample Type Confirmation:

  VPS4B is supported by BioGPS gene expression data to be expressed in OVCAR3

Target Info

• Gene Symbol: VPS4B
• Gene Full Name: Vacuolar protein sorting 4 homolog B (S. cerevisiae)
• Alias Symbols: MIG1, SKD1, SKD1B, VPS4-2
• NCBI Gene Id: 9525
• Protein Name: Vacuolar protein sorting-associated protein 4B
• Description of Target: The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. Mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be a yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 18; the gene for the other resides on chromosome 16.
• Uniprot ID: O75351
• Protein Accession #: NP_004860
• Nucleotide Accession #: NM_004869
• Protein Size (# AA): 444
• Molecular Weight: 49kDa
• Protein Interactions: ZFYVE19; CHMP5; UBC; HTRA2; CHMP4A; TTLL12; AHCYL1; SSSCA1; YAP1; UBE4B; PDCD6IP; USP34; VPS26A; USP8; ZPR1; NUP214; TYMS; RAB5B; IGBP1; TTC9C; ZNF585B; UBQLN4; UBXN1; UBQLN1; CUL3; CHMP2A; CHMP1A; ELAVL1; BABAM1; CHMP1B; VPS4A; VPS4; LIP5;