Catalog No: OAPB02067
Size:100UG
Price: $536.00
SKU
OAPB02067
Availability: Domestic: within 1-2 weeks delivery | International: 1-2 weeks
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  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
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Datasheets/ManualsPrintable datasheet for Vinculin Antibody - N-terminal (OAPB02067) (OAPB02067)
Product Info
Predicted Species ReactivityChicken|Human|Mouse|Porcine|Rabbit|Rat
Product FormatLiquid. Vinculin Antibody is supplied in PBS containing 0.02% sodium azide.
ClonalityMonoclonal
IsotypeIgG
HostMouse
ConjugationUnconjugated
ApplicationEnzyme-linked immunosorbent assay|Western blot
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenVinculin antibody was raised against a 23 amino acid peptide near the amino terminus of human Vinculin. The immunogen is located within amino acids 50 - 100 of Vinculin.
PurificationProtein A Purified
Concentration1 mg/ml
Gene SymbolVCL
Gene Full Namevinculin
Alias SymbolsCMD1W;CMH15;epididymis luminal protein 114;epididymis secretory sperm binding protein;HEL114;metavinculin;meta-vinculin;MV;MVCL;vinculin;vinculin isoform meta-VCL.
NCBI Gene Id7414
Protein Namevinculin isoform VCL [Homo sapiens]
Description of TargetVinculin is a cytoskeletal protein that plays an important role in the regulation of focal adhesions and embryonic development (1). Three structural vinculin domains include an amino-terminal head, a short flexible proline-rich region and a carboxy-terminal tail (2). Expression of vinculin were shown to be affected by the level of actin expression (2,3). Vinculin deficiencies are associated with a decrease in cell adhesion and an increase in cell motility, suggesting a possible role in metastatic growth (4). Defects in VCL are the cause of cardiomyopathy dilated type 1W (CMD1W) (5).
Uniprot IDP18206
Protein Accession #https://www.ncbi.nlm.nih.gov/protein/NP_003364
Nucleotide Accession #NM_003373.3
Molecular WeightPredicted: 117 kDa Observed: 120 kDa
  1. What is the species homology for "Vinculin Antibody - N-terminal (OAPB02067)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Chicken|Human|Mouse|Porcine|Rabbit|Rat".

  2. How long will it take to receive "Vinculin Antibody - N-terminal (OAPB02067)"?

    This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".

  3. What buffer format is "Vinculin Antibody - N-terminal (OAPB02067)" provided in?

    This item is provided in "Liquid. Vinculin Antibody is supplied in PBS containing 0.02% sodium azide.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "Vinculin Antibody - N-terminal (OAPB02067)"?

    This target may also be called "CMD1W;CMH15;epididymis luminal protein 114;epididymis secretory sperm binding protein;HEL114;metavinculin;meta-vinculin;MV;MVCL;vinculin;vinculin isoform meta-VCL." in publications.

  5. What is the shipping cost for "Vinculin Antibody - N-terminal (OAPB02067)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "Vinculin Antibody - N-terminal (OAPB02067)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "Vinculin Antibody - N-terminal (OAPB02067)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "Predicted: 117 kDa Observed: 120 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "Vinculin Antibody - N-terminal (OAPB02067)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "VCL"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "VCL"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "VCL"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "VCL"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "VCL"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "VCL"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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