Catalog No: OABF01328
Size:100 ul
Price: $399.00
SKU
OABF01328
Availability: Domestic: within 1-2 weeks delivery | International: within 1-2 weeks delivery
Bulk
Order
Aviva's
Satisfaction
Guarantee
Contact Us:
Shipping Info:
  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
  • Contact us for international orders.
Datasheets/ManualsPrintable datasheet for OABF01328
Product Info
Predicted Species ReactivityHuman, Mouse, Rat
Product FormatLiquid. 1% BSA, 50% glycerol and 0.09% sodium azide.
ClonalityPolyclonal
IsotypeIgG
HostRabbit
ConjugationUnconjugated
ApplicationWB, IHC-P
Additional InformationSubcellular location: Cytoplasm
Reconstitution and StorageStore at -20C for 12 months.
ImmunogenKLH conjugated synthetic peptide derived from human Villin, aa. 345-395/827.
PurificationPurified by Protein A.
Concentration1ug/ul
Intended UseFor research use only. Not intended for diagnostic or therapeutic use.
Application InfoWB: 1:100 - 1000
IHC-P: 1:100 - 500
Gene SymbolVIL1
Gene Full Namevillin 1
Alias SymbolsVIL, D2S1471
NCBI Gene Id7429
Description of TargetEpithelial cell-specific Ca(2+)-regulated actin-modifying protein that modulates the reorganization of microvillar actin filaments. Plays a role in the actin nucleation, actin filament bundle assembly, actin filament capping and severing. Binds phosphatidylinositol 4,5-bisphosphate (PIP2) and lysophosphatidic acid (LPA); binds LPA with higher affinity than PIP2. Binding to LPA increases its phosphorylation by SRC and inhibits all actin-modifying activities. Binding to PIP2 inhibits actin-capping and -severing activities but enhances actin-bundling activity. Regulates the intestinal epithelial cell morphology, cell invasion, cell migration and apoptosis. Protects against apoptosis induced by dextran sodium sulfate (DSS) in the gastrointestinal epithelium. Appears to regulate cell death by maintaining mitochondrial integrity. Enhances hepatocyte growth factor (HGF)-induced epithelial cell motility, chemotaxis and wound repair. Upon S.flexneri cell infection, its actin-severing activity enhances actin-based motility of the bacteria and plays a role during the dissemination.
Uniprot IDP09327
  1. What is the species homology for "VIL1 Antibody (OABF01328)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat".

  2. How long will it take to receive "VIL1 Antibody (OABF01328)"?

    This item is available "Domestic: within 1-2 weeks delivery | International: within 1-2 weeks delivery".

  3. What buffer format is "VIL1 Antibody (OABF01328)" provided in?

    This item is provided in "Liquid. 1% BSA, 50% glycerol and 0.09% sodium azide.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "VIL1 Antibody (OABF01328)"?

    This target may also be called "VIL, D2S1471" in publications.

  5. What is the shipping cost for "VIL1 Antibody (OABF01328)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "VIL1 Antibody (OABF01328)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "VIL1 Antibody (OABF01328)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "VIL1 Antibody (OABF01328)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "VIL1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "VIL1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "VIL1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "VIL1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "VIL1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "VIL1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

Write Your Own Review
You're reviewing:VIL1 Antibody (OABF01328)
Your Rating
We found other products you might like!