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VEGFA Antibody - C-terminal region : FITC (ARP60980_P050-FITC)

100 ul
$289.00
In Stock
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Conjugation Options

ARP60980_P050 Unconjugated

ARP60980_P050-HRP Conjugated

ARP60980_P050-Biotin Conjugated

Gene Symbol:
VEGFA
NCBI Gene Id:
7422
Swissprot Id:
P15692-12
Alias Symbols:
Name=VEGFA,
Replacement Item:
This antibody may replace item sc-152 from Santa Cruz Biotechnology.
Description of Target:
This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms.
Protein Size (# AA):
327
Molecular Weight:
35kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express VEGFA.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express VEGFA.
Immunogen:
The immunogen is a synthetic peptide directed towards the C-terminal region of Human VEGFA
Predicted Species Reactivity:
Human
Peptide Sequence:
Synthetic peptide located within the following region: ECRPKKDRARQEKKSVRGKGKGQKRKRKKSRYKSWSVYVGARCCLMPWSL
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution and Storage:
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Concentration:
1 mg/ml
Protein Interactions:
ILF3; HNRNPL; NRP1; FLT1; LYVE1; KDR; PRRG4; VPS35; U2AF1; Flt4; ELAVL1; CRYAB; HNRNPD; HGS; UBC; HSP90AA1; HSPA4; YBX3; ADAMTS1; IGFBP7; NRP2; VEGFB; SEMA3F; PGF; EPHB2; TNXB; GPC1; VTN; VEGFA; SPARC; AKT1; YBX1; CTGF; RB1; HIF1A;
Blocking Peptide:
For anti-VEGFA (ARP60980_P050-FITC) antibody is Catalog # AAP60980
Datasheets/Manuals:
Printable datasheet for anti-VEGFA (ARP60980_P050-FITC) antibody
Conjugation:
FITC (FAM): Excitation 495 nm/ Emission 520 nm

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