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VDAC1 Antibody (OAGA01068)

100 ul
$409.00
In Stock
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Predicted Species Reactivity:
Human
Product Format:
Liquid
Clonality:
Polyclonal
Isotype:
IgG
Host:
Rabbit
Application:
IHC-FFPE, WB
Additional Information:
Background: This gene encodes a voltage-dependent anion channel protein that is a major component of the outer mitochondrial membrane. The encoded protein facilitates the exchange of metabolites and ions across the outer mitochondrial membrane and may regulate mitochondrial functions. This protein also forms channels in the plasma membrane and may be involved in transmembrane electron transport. Alternate splicing results in multiple transcript variants. Multiple pseudogenes of this gene are found on chromosomes 1, 2 3, 6, 9, 12, X and Y.
:::
Positive Controls: A431, H1299, HeLa, HepG2
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Cellular Localization: Mitochondrion outer membrane, Cell membrane
Reconstitution and Storage:
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Gene Symbol:
VDAC1
Official Gene Full Name:
Voltage-dependent anion-selective channel protein 1
NCBI Gene Id:
7416
Protein Name:
Voltage-dependent anion-selective channel protein 1
Swissprot Id:
P21796
Protein Accession #:
NP_003365.1
Alias Symbols:
MGC111064 antibody, PORIN antibody, VDAC-1 antibody, VDAC1 antibody, outer mitochondrial membrane protein porin 1 antibody, voltage-dependent anion-selective channel protein 1 antibody, porin 31HM antibody, plasmalemmal porin antibody, porin 31HL antibody
Replacement Item:
This antibody may replace item sc-171785 from Santa Cruz Biotechnology.
Molecular Weight:
31 kDa
Purification:
Purified by antigen-affinity chromatography.
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express VDAC1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express VDAC1.
Immunogen:
Recombinant fragment corresponding to a region within amino acids 1 and 211 of VDAC1 (Uniprot ID#P21796)
Concentration:
0.35 mg/ml
Datasheets/Manuals:
Printable datasheet for anti-VDAC1 antibody - OAGA01068
Application Info:
Suggested starting dilutions are as follows: WB: 1:500-1:3000, IHC-P: 1:100-1:1000 [suggested antigen retrieval using heat mediated 10mM Citrate buffer (pH6.0) or Tris-EDTA buffer (pH8.0)]. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Storage Buffer:
0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

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