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VCL Antibody - C-terminal region : FITC (ARP61098_P050-FITC)
Datasheets/Manuals | Printable datasheet for anti-VCL (ARP61098_P050-FITC) antibody |
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Predicted Species Reactivity | Human |
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Product Format | Liquid. Purified antibody supplied in 1x PBS buffer. |
Clonality | Polyclonal |
Host | Rabbit |
Conjugation | FITC: Fluorescein Isothiocyanate |
Application | WB |
Reconstitution and Storage | All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
Immunogen | The immunogen is a synthetic peptide directed towards the C-terminal region of Human VINC |
Purification | Affinity purified |
Peptide Sequence | Synthetic peptide located within the following region: QPQMLVAGATSIARRANRILLVAKREVENSEDPKFREAVKAASDELSKTI |
Concentration | 0.5 mg/ml |
Blocking Peptide | For anti-VCL (ARP61098_P050-FITC) antibody is Catalog # AAP61098 |
Gene Symbol | VCL |
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Gene Full Name | vinculin |
Alias Symbols | MV, MVCL, CMD1W, CMH15, HEL114 |
NCBI Gene Id | 7414 |
Protein Name | vinculin |
Description of Target | Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. |
Uniprot ID | P18206 |
Protein Accession # | NP_054706 |
Protein Size (# AA) | 1134 |
Molecular Weight | 124kDa |
Protein Interactions | VCL; UBC; TEKT1; SUMO2; ASB7; CTPS1; GINS3; UBFD1; ISOC1; DCPS; ERP44; PDCD10; FERMT2; YWHAQ; TUBB3; PDIA4; STK24; YWHAZ; YWHAH; YWHAG; YWHAE; XPO1; SNRPF; RAP1GDS1; PPP5C; PPP1R2; PFAS; PDHA1; MSN; HSPA9; HSPA5; GSS; SFN; GNAI3; G6PD; EIF5; ECHS1; TBCB; |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "VCL Antibody - C-terminal region : FITC (ARP61098_P050-FITC)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
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How long will it take to receive "VCL Antibody - C-terminal region : FITC (ARP61098_P050-FITC)"?
This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".
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What buffer format is "VCL Antibody - C-terminal region : FITC (ARP61098_P050-FITC)" provided in?
This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "VCL Antibody - C-terminal region : FITC (ARP61098_P050-FITC)"?
This target may also be called "MV, MVCL, CMD1W, CMH15, HEL114" in publications.
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What is the shipping cost for "VCL Antibody - C-terminal region : FITC (ARP61098_P050-FITC)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "VCL Antibody - C-terminal region : FITC (ARP61098_P050-FITC)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "VCL Antibody - C-terminal region : FITC (ARP61098_P050-FITC)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "124kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "VCL Antibody - C-terminal region : FITC (ARP61098_P050-FITC)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "VCL"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "VCL"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "VCL"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "VCL"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "VCL"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "VCL"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.