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VCL Antibody - C-terminal region : FITC (ARP61098_P050-FITC)

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100 ul
$289.00
In Stock
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Conjugation Options

ARP61098_P050 Unconjugated

ARP61098_P050-HRP Conjugated

ARP61098_P050-Biotin Conjugated

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Gene Symbol:
VCL
Official Gene Full Name:
vinculin
NCBI Gene Id:
7414
Protein Name:
vinculin
Swissprot Id:
P18206
Protein Accession #:
NP_054706
Alias Symbols:
MV, MVCL, CMD1W, CMH15, HEL114
Description of Target:
Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.
Protein Size (# AA):
1134
Molecular Weight:
124kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity purified
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express VCL.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express VCL.
Immunogen:
The immunogen is a synthetic peptide directed towards the C-terminal region of Human VINC
Predicted Species Reactivity:
Human
Peptide Sequence:
Synthetic peptide located within the following region: QPQMLVAGATSIARRANRILLVAKREVENSEDPKFREAVKAASDELSKTI
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution and Storage:
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Concentration:
0.5 mg/ml
Protein Interactions:
VCL; UBC; TEKT1; SUMO2; ASB7; CTPS1; GINS3; UBFD1; ISOC1; DCPS; ERP44; PDCD10; FERMT2; YWHAQ; TUBB3; PDIA4; STK24; YWHAZ; YWHAH; YWHAG; YWHAE; XPO1; SNRPF; RAP1GDS1; PPP5C; PPP1R2; PFAS; PDHA1; MSN; HSPA9; HSPA5; GSS; SFN; GNAI3; G6PD; EIF5; ECHS1; TBCB;
Blocking Peptide:
For anti-VCL (ARP61098_P050-FITC) antibody is Catalog # AAP61098
Datasheets/Manuals:
Printable datasheet for anti-VCL (ARP61098_P050-FITC) antibody
Conjugation:
FITC (FAM): Excitation 495 nm/ Emission 520 nm

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