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Catalog No: OAAN02824
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OAAN02824
Availability: Domestic: within 1-2 weeks delivery | International: 1-2 weeks
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  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
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Datasheets/ManualsPrintable datasheet for anti-VAV1 (OAAN02824)
Product Info
Predicted Species ReactivityHuman, Mouse, Rat
Product FormatLiquid
ClonalityPolyclonal
IsotypeIgG
HostRabbit
ConjugationUnconjugated
ApplicationWB
Reconstitution and StorageStore at -20C. Avoid repeated freeze/thaw cycles.
ImmunogenA phospho-Serpecific peptide corresponding-Thro residues-Serurrounding-Tyr174 of human VAV1
PurificationAffinity purified against immunogen
Preservative0.02% Sodium Azide
Target Post-Translational ModificationPhospho-Tyr174
Application InfoWB: 1:500 - 1:2,000
Storage BufferPBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Gene SymbolVAV1
Gene Full Namevav guanine nucleotide exchange factor 1
Alias SymbolsVAV
NCBI Gene Id7409
Protein NameProto-oncogene vav
Description of TargetThis gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Uniprot IDP15498
Protein Accession #NP_001245136.1
Nucleotide Accession #NM_001258207.1
Molecular Weight95 kDa
  1. What is the species homology for "VAV1 Antibody (Phospho-Tyr174) (OAAN02824)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat".

  2. How long will it take to receive "VAV1 Antibody (Phospho-Tyr174) (OAAN02824)"?

    This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".

  3. What buffer format is "VAV1 Antibody (Phospho-Tyr174) (OAAN02824)" provided in?

    This item is provided in "Liquid".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "VAV1 Antibody (Phospho-Tyr174) (OAAN02824)"?

    This target may also be called "VAV" in publications.

  5. What is the shipping cost for "VAV1 Antibody (Phospho-Tyr174) (OAAN02824)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "VAV1 Antibody (Phospho-Tyr174) (OAAN02824)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "VAV1 Antibody (Phospho-Tyr174) (OAAN02824)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "95 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "VAV1 Antibody (Phospho-Tyr174) (OAAN02824)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "VAV1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "VAV1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "VAV1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "VAV1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "VAV1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "VAV1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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