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Catalog No: OAAL00352
Size:100UG
Price: $420.00
SKU
OAAL00352
Availability: Domestic: within 2-3 week delivery | International: 2-3 weeks
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  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
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Datasheets/ManualsPrintable datasheet for VAV1 Antibody (OAAL00352)
Product Info
Predicted Species ReactivityHuman, Mouse
Product FormatLiquid
ClonalityMonoclonal
Clone1A6
IsotypeIgG2a Kappa
HostMouse
ApplicationEnzyme-linked immunosorbent assay|Western blot
Reconstitution and StorageStore at -20C or lower. Aliquot to avoid repeated freezing and thawing.
ImmunogenVAV1 (AAH13361, 681 a.a. ~ 790 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Peptide SequenceRGLTELVEFYQQNSLKDCFKSLDTTLQFPFKEPEKRTISRPAVGSTKYFGTAKARYDFCARDRSELSLKEGDIIKILNKKGQQGWWRGEIYGRVGWFPANYVEEDYSEYC
FormulationIn 1x PBS, pH 7.4
Gene SymbolVAV1
Gene Full Namevav guanine nucleotide exchange factor 1
Alias Symbolsproto-oncogene vav;VAV;vav 1 guanine nucleotide exchange factor;vav 1 oncogene.
NCBI Gene Id7409
Protein NameHomo sapiens vav 1 guanine nucleotide exchange factor, mRNA (cDNA clone MGC:15356 IMAGE:3842829), complete cds|VAV1 protein [Homo sapiens]
Description of TargetThe protein encoded by this proto-oncogene is a member of the Dbl family of guanine nucleotide exchange factors (GEF) for the Rho family of GTP binding proteins. The protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. This particular GEF has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. [provided by RefSeq
Protein Accession #https://www.ncbi.nlm.nih.gov/protein/AAH13361
Nucleotide Accession #https://www.ncbi.nlm.nih.gov/nuccore/BC013361
  1. What is the species homology for "VAV1 Antibody (OAAL00352)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse".

  2. How long will it take to receive "VAV1 Antibody (OAAL00352)"?

    This item is available "Domestic: within 2-3 week delivery | International: 2-3 weeks".

  3. What buffer format is "VAV1 Antibody (OAAL00352)" provided in?

    This item is provided in "Liquid".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "VAV1 Antibody (OAAL00352)"?

    This target may also be called "proto-oncogene vav;VAV;vav 1 guanine nucleotide exchange factor;vav 1 oncogene." in publications.

  5. What is the shipping cost for "VAV1 Antibody (OAAL00352)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "VAV1 Antibody (OAAL00352)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "VAV1 Antibody (OAAL00352)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "VAV1 Antibody (OAAL00352)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "VAV1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "VAV1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "VAV1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "VAV1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "VAV1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "VAV1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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