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VARS antibody - middle region (ARP46151_P050)

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100 ul
$289.00
In Stock

Conjugation Options

ARP46151_P050-FITC Conjugated

ARP46151_P050-HRP Conjugated

ARP46151_P050-Biotin Conjugated

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Gene Symbol:
VARS
NCBI Gene Id:
7407
Official Gene Full Name:
Valyl-tRNA synthetase
Protein Name:
Valine--tRNA ligase
Swissprot Id:
P26640
Protein Accession #:
NP_006286
Nucleotide Accession #:
NM_006295
Alias Symbols:
G7A, VARS2, VARS1
Description of Target:
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. VARS belongs to class-I aminoacyl-tRNA synthetase family and is located in the class III region of the major histocompatibility complex.Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. The protein encoded by this gene belongs to class-I aminoacyl-tRNA synthetase family and is located in the class III region of the major histocompatibility complex. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Protein Size (# AA):
1264
Molecular Weight:
140kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
WB, IHC
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express VARS.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express VARS.
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of human VARS
Species Reactivity:
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish
Predicted Homology Based on Immunogen Sequence:
Cow: 100%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 86%; Zebrafish: 86%
Complete computational species homology data:
Anti-VARS (ARP46151_P050)
Peptide Sequence:
Synthetic peptide located within the following region: VFDEFVDMDFGTGAVKITPAHDQNDYEVGQRHGLEAISIMDSRGALINVP
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
CALCOCO2; SUMO2; SART3; STAU1; UBC; EED; CCT4; KNTC1; AIMP1; CCT3; QARS; EEF1G; EEF1D; EEF1B2; FBXO6; YWHAQ; MAPK11; VCAM1; ITGA4; FN1; LARS; CAD; UBD; SHC1; CUL3; CDK2; CHD7; CACNA1A; ATG101; OTUD5; DMWD; EEF1A1; EEF1A2; TRAF6; TFE3; HLA-B; EPB41;
Blocking Peptide:
For anti-VARS (ARP46151_P050) antibody is Catalog # AAP46151 (Previous Catalog # AAPS17009)
Datasheets/Manuals:
Printable datasheet for anti-VARS (ARP46151_P050) antibody
Sample Type Confirmation:

VARS is strongly supported by BioGPS gene expression data to be expressed in 721_B

Target Reference:
Ewing,R.M., Mol. Syst. Biol. 3, 89 (2007)
Publications:

Duarte, M. & Videira, A. Defective valyl-tRNA synthetase hampers the mitochondrial respiratory chain in Neurospora crassa. Biochem. J. 448, 297-306 (2012). WB, IHC, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish 22957697

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