USP6NL Antibody (OAAF04433)

Catalog No: OAAF04433

Size:100 ug

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using USP6NL Antibody. The picture on the right is treated with the synthesized peptide.

Product Info

• Predicted Species Reactivity: Human|Mouse|Rat
• Product Format: Liquid
• Clonality: Polyclonal
• Host: Rabbit
• Application: Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin
• Reconstitution and Storage: -20°C
• Immunogen: The antiserum was produced against synthesized peptide derived from human USP6NL.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Specificity: USP6NL antibody detects endogenous levels of total USP6NL protein.
• Formulation: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Dilution: The optimal working dilution should be determined by the end user.
• Application Info: IHC: 1:50~1:100; ELISA: 1:10000
• Reference: Wong W.T., Oncogene 12:2563-2571(1996).
  Nomura N., DNA Res. 1:27-35(1994).
  Lanzetti L., Nature 408:374-377(2000)

Target Info

• Gene Symbol: USP6NL
• Gene Full Name: USP6 N-terminal like
• Alias Symbols: related to the N-terminus of tre;RNTRE;TRE2NL;USP6 N-terminal-like protein;USP6NL-IT1.
• NCBI Gene Id: 9712
• Protein Name: USP6 N-terminal-like protein
• Description of Target: Acts as a GTPase-activating protein for RAB5A and RAB43. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for structural integrity of the Golgi complex.
• Uniprot ID: Q92738
• Protein Accession #: NP_001073960.1
• Molecular Weight: 94 kDa