USP22 Antibody - C-terminal region (OAAB17747)

Catalog No: OAAB17747

Size:400ul

USP22 Antibody (C-term) (Cat. #OAAB17747) western blot analysis in Daudi cell line lysates (35ug/lane).
This demonstrates the USP22 antibody detected the USP22 protein (arrow).

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid. PBS with 0.09% (W/V) sodium azide.
• Clonality: Monoclonal
• Isotype: IgG1
• Host: Mouse
• Application: WB
  Cellular Location: Nucleus.
  Tissue Location: Moderately expressed in various tissues including heart and skeletal muscle, and weakly expressed in lung and liver.
  
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: Purified His-tagged USP22 protein was used to produced this monoclonal antibody.
• Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.
• Concentration: 0.5 mg/ml
• Application Info: WB: 1:1000
• Intended Use: USP22 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.

Target Info

• Reference: Kikuno R., et al. DNA Res. 6:197-205(1999).
  Bechtel S., et al. BMC Genomics 8:399-399(2007).
  Lee H.-J., et al. Gene Expr. Patterns 6:277-284(2006).
  Zhao Y., et al. Mol. Cell 29:92-101(2008).
  Zhang X.-Y., et al. Mol. Cell 29:102-111(2008).
• Gene Symbol: USP22
• Alias Symbols: USP3L
• NCBI Gene Id: 23326
• Description of Target: Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation and cell cycle progression.
• Uniprot ID: Q9UPT9
• Protein Accession #: NP_056091.1
• Molecular Weight: 59961 Da