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- $55: Antibody & Protein in US
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Datasheets/Manuals | Printable datasheet for OAAB15734 |
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Predicted Species Reactivity | Human, Mouse, Rat, Cow |
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Product Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Clonality | Polyclonal |
Isotype | Ig |
Host | Rabbit |
Application | WB, IHC |
Additional Information | Precautions: USP2 Antibody (C-term L523) is for research use only and not for use in diagnostic or therapeutic procedures. |
:: | Function: Hydrolase that deubiquitinates polyubiquitinated target proteins such as MDM2, MDM4 and CCND1. Isoform 1 and isoform 4 possess both ubiquitin-specific peptidase and isopeptidase activities. Deubiquitinates MDM2 without reversing MDM2-mediated p53/TP53 ubiquitination and thus indirectly promotes p53/TP53 degradation and limits p53 activity. Has no deubiquitinase activity against p53/TP53. Prevents MDM2-mediated degradation of MDM4. Plays a role in the G1/S cell-cycle progression in normal and cancer cells. Plays a role in the regulation of myogenic differentiation of embryonic muscle cells |
:: | Cellular Location: Cytoplasm (By similarity). Cytoplasm, perinuclear region (By similarity). Note=Localizes in the spermatid head in late-elongating spermatids in the thin area between the outer acrosomal membrane and the plasma membrane (By similarity) Tissue Location: Expressed in mesangial cells of the kidney and in different types of glomerulonephritides (at protein level) |
Reconstitution and Storage | Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles. |
Immunogen | This USP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 508-538 amino acids from the C-terminal region of human USP2. |
Predicted Homology Based on Immunogen Sequence | Cow; Human; Mouse; Rat |
Concentration | Approximately 0.5mg/ml. Actual concentration varies with each lot. |
Sample Type Confirmation | USP2 is strongly supported by BioGPS gene expression data to be expressed in K562 |
Application Info | IHC-P: 1:100 WB: 1:2000 IHC-P: 1:50~100 |
Gene Symbol | USP2 |
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Alias Symbols | USP9, UBP41 |
NCBI Gene Id | 9099 |
Protein Name | Ubiquitin carboxyl-terminal hydrolase 2 |
Description of Target | Purified Rabbit Polyclonal Antibody (Pab) |
Uniprot ID | O75604 |
Protein Accession # | NP_001230688.1 |
Molecular Weight | 68072 Da |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "USP2 Antibody - C-terminal region (Phospho-L523) (OAAB15734)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow".
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How long will it take to receive "USP2 Antibody - C-terminal region (Phospho-L523) (OAAB15734)"?
This item is available "Domestic: within 1-2 week delivery | International: within 1-2 week delivery".
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What buffer format is "USP2 Antibody - C-terminal region (Phospho-L523) (OAAB15734)" provided in?
This item is provided in "Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "USP2 Antibody - C-terminal region (Phospho-L523) (OAAB15734)"?
This target may also be called "USP9, UBP41" in publications.
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What is the shipping cost for "USP2 Antibody - C-terminal region (Phospho-L523) (OAAB15734)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "USP2 Antibody - C-terminal region (Phospho-L523) (OAAB15734)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "USP2 Antibody - C-terminal region (Phospho-L523) (OAAB15734)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "68072 Da".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "USP2 Antibody - C-terminal region (Phospho-L523) (OAAB15734)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "USP2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "USP2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "USP2"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "USP2"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "USP2"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "USP2"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.