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USH1C Antibody - C-terminal region (ARP96739_P050)

100 ul
$289.00
In Stock
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Gene Symbol:
USH1C
Official Gene Full Name:
Usher syndrome 1C
NCBI Gene Id:
10083
Protein Name:
harmonin
Swissprot Id:
Q9Y6N9-3
Protein Accession #:
NP_001284693.1
Nucleotide Accession #:
NM_001297764.1
Alias Symbols:
PDZ73, AIE-75, DFNB18, PDZ-45, PDZ-73, PDZD7C, DFNB18A, NY-CO-37, NY-CO-38, ush1cpst, PDZ-73/NY-CO-38
Description of Target:
Anchoring/scaffolding protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal development and maintenance of cochlear hair cell bundles (By similarity). As part of the intermicrovillar adhesion complex/IMAC plays a role in brush border differentiation, controlling microvilli organization and length. Probably plays a central regulatory role in the assembly of the complex, recruiting CDHR2, CDHR5 and MYO7B to the microvilli tips.
Protein Size (# AA):
403
Molecular Weight:
46 kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity purified
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express HIBCH.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express USH1C.
Immunogen:
The immunogen is a synthetic peptide directed towards the C terminal region of human USH1C
Predicted Species Reactivity:
Human
Tested Species Reactivity:
Human
Peptide Sequence:
Synthetic peptide located within the following region: QRQELLMQKRLAMESNKILQEQQEMERQRRKEIAQKAAEENERYRKEMEQ
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking Peptide:
For anti-USH1C (ARP96739_P050) antibody is Catalog # AAP96739
Datasheets/Manuals:
Printable datasheet for anti-USH1C (ARP96739_P050) antibody

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