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USH1C Antibody - C-terminal region (ARP96739_P050)

Catalog#: ARP96739_P050
Domestic: within 24 hours delivery | International: 3-5 business days
More Information
Tested Species ReactivityHuman
Predicted Species ReactivityHuman
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the C terminal region of human USH1C
PurificationAffinity purified
Peptide SequenceSynthetic peptide located within the following region: QRQELLMQKRLAMESNKILQEQQEMERQRRKEIAQKAAEENERYRKEMEQ
ConcentrationBatch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking PeptideFor anti-USH1C (ARP96739_P050) antibody is Catalog # AAP96739
Datasheets/ManualsPrintable datasheet for anti-USH1C (ARP96739_P050) antibody
Gene SymbolUSH1C
Official Gene Full NameUsher syndrome 1C
Alias SymbolsPDZ73, AIE-75, DFNB18, PDZ-45, PDZ-73, PDZD7C, DFNB18A, NY-CO-37, NY-CO-38, ush1cpst, PDZ-73/NY-CO-38
NCBI Gene Id10083
Protein Nameharmonin
Description of TargetAnchoring/scaffolding protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal development and maintenance of cochlear hair cell bundles (By similarity). As part of the intermicrovillar adhesion complex/IMAC plays a role in brush border differentiation, controlling microvilli organization and length. Probably plays a central regulatory role in the assembly of the complex, recruiting CDHR2, CDHR5 and MYO7B to the microvilli tips.
Swissprot IdQ9Y6N9-3
Protein Accession #NP_001284693.1
Nucleotide Accession #NM_001297764.1
Protein Size (# AA)403
Molecular Weight46 kDa
Tissue ToolFind tissues and cell lines supported by DNA array analysis to express HIBCH.
RNA SeqFind tissues and cell lines supported by RNA-seq analysis to express USH1C.
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