UPK1B Antibody - middle region (OAAB06324)

Catalog No: OAAB06324

Size:400UL

Western blot analysis of UPK1B Antibody (Center) in K562 cell lysates (35ug/lane). UPK1B (arrow) was detected using the purified Pab.

UPK1B Antibody (Center) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the UPK1B Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

UPK1B Antibody (Center) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Product Info

• Predicted Species Reactivity: Human|Mouse
• Product Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
• Clonality: Polyclonal
• Isotype: Rabbit Ig
• Host: Rabbit
• Application: FC,IHC-P,WB
• Additional Information: Function: Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions (By similarity).
  
  Cellular Location: Membrane; Multi-pass membrane protein.
  Tissue Location: Bladder epithelium.
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This UPK1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 159-188 amino acids from the Central region of human UPK1B.
• Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
• Predicted Homology Based on Immunogen Sequence: Human
• Concentration: Approximately 0.5mg/ml. Actual concentration varies with each lot.
• Application Info: WB: 1:1000
  IHC-P: 1:50~100
  FC: 1:10~50
• Other Applications Image 1 Data: UPK1B Antibody (Center) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Target Info

• Gene Symbol: UPK1B
• Gene Full Name: uroplakin 1B
• Alias Symbols: tetraspan, tetraspanin-20, tspan-20, TSPAN20, UP1b, UPIB, UPK1, uroplakin Ib, uroplakin-1b.
• NCBI Gene Id: 7348
• Protein Name: Uroplakin-1b|uroplakin-1b [Homo sapiens]
• Description of Target: Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions (By similarity).
• Uniprot ID: O75841
• Protein Accession #: https://www.ncbi.nlm.nih.gov/protein/NP_008883.2
• Molecular Weight: 29643