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Datasheets/Manuals | Printable datasheet for ULK2 Antibody - N-terminal (OAPB01754) (OAPB01754) |
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Predicted Species Reactivity | Human|Mouse |
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Product Format | Liquid. ULK2 Antibody is supplied in PBS containing 0.02% sodium azide. |
Clonality | Polyclonal |
Isotype | IgG |
Host | Rabbit |
Conjugation | Unconjugated |
Application | Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot |
Reconstitution and Storage | For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Immunogen | ULK2 antibody was raised against a 17 amino acid peptide near the center of human ULK2 . The immunogen is located within amino acids 480 - 530 of ULK2. |
Purification | Affinity Purified |
Concentration | 1 mg/ml |
Gene Symbol | ULK2 |
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Gene Full Name | unc-51 like autophagy activating kinase 2 |
Alias Symbols | ATG1B;serine/threonine-protein kinase ULK2;Unc51.2;Unc-51-like kinase 2. |
NCBI Gene Id | 9706 |
Protein Name | Serine/threonine-protein kinase ULK2|serine/threonine-protein kinase ULK2 [Homo sapiens] |
Description of Target | Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. Part of regulatory feedback loops in autophagy: acts both as a downstream effector and a negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR. Activated via phosphorylation by AMPK, also acts as a negative regulator of AMPK through phosphorylation of the AMPK subunits PRKAA1, PRKAB2 and PRKAG1. May phosphorylate ATG13/KIAA0652, FRS2, FRS3 and RPTOR; however such data need additional evidences. Not involved in ammonia-induced autophagy or in autophagic response of cerebellar granule neurons (CGN) to low potassium concentration. Plays a role early in neuronal differentiation and is required for granule cell axon formation: may govern axon formation via Ras-like GTPase signaling and through regulation of the Rab5-mediated endocytic pathways within developing axons. |
Uniprot ID | Q8IYT8 |
Protein Accession # | https://www.ncbi.nlm.nih.gov/protein/NP_055498 |
Nucleotide Accession # | NM_001142610.1 |
Molecular Weight | Predicted: 105, 114 kDa Observed: 100 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "ULK2 Antibody - N-terminal (OAPB01754)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse".
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How long will it take to receive "ULK2 Antibody - N-terminal (OAPB01754)"?
This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".
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What buffer format is "ULK2 Antibody - N-terminal (OAPB01754)" provided in?
This item is provided in "Liquid. ULK2 Antibody is supplied in PBS containing 0.02% sodium azide.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "ULK2 Antibody - N-terminal (OAPB01754)"?
This target may also be called "ATG1B;serine/threonine-protein kinase ULK2;Unc51.2;Unc-51-like kinase 2." in publications.
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What is the shipping cost for "ULK2 Antibody - N-terminal (OAPB01754)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "ULK2 Antibody - N-terminal (OAPB01754)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "ULK2 Antibody - N-terminal (OAPB01754)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "Predicted: 105, 114 kDa Observed: 100 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "ULK2 Antibody - N-terminal (OAPB01754)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "ULK2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "ULK2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "ULK2"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "ULK2"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "ULK2"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "ULK2"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.