UCHL3 Antibody - N-terminal region : HRP (ARP58689_P050-HRP)

Catalog No: ARP58689_P050-HRP

Size:100ul

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Goat, Guinea Pig, Horse, Rabbit, Zebrafish
• Product Format: Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
• Clonality: Polyclonal
• Host: Rabbit
• Conjugation: HRP: Horseradish Peroxidase
• Application: IHC, WB
• Additional Information: IHC Information: Placenta
• Reconstitution and Storage: All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human UCHL3
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Goat: 82%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%
• Peptide Sequence: Synthetic peptide located within the following region: MEGQRWLPLEANPEVTNQFLKQLGLHPNWQFVDVYGMDPELLSMVPRPVC
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-UCHL3 (ARP58689_P050-HRP) antibody is Catalog # AAP58689 (Previous Catalog # AAPP35936)
• Reference: Lim,J., (2006) Cell 125 (4), 801-814

Target Info

• Gene Symbol: UCHL3
• Gene Full Name: Ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
• Alias Symbols: UCH-L3
• NCBI Gene Id: 7347
• Protein Name: Ubiquitin carboxyl-terminal hydrolase isozyme L3
• Description of Target: UCHL3 is an ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of either ubiquitin or NEDD8.
• Uniprot ID: P15374
• Protein Accession #: NP_005993
• Nucleotide Accession #: NM_006002
• Protein Size (# AA): 230
• Molecular Weight: 25kDa
• Protein Interactions: UBC; CDH1; BAG3; LONRF1; TRIM27; TTC9C; NT5DC1; UBR1; UNK; UBL7; ZFYVE19; USP48; UBA6; ZNF593; UBQLN1; VPS33B; UBXN7; AHCYL1; SSSCA1; YAP1; UBE4B; USP34; ZRANB2; ATP6V1F; USP9X; USP5; ZYX; UBE2V1; UBE2L3; UBE2A; TTC1; TSN; SULT1A1; SNRPD1; PCMT1; PBX1; CS