Catalog No: ARP54958_P050
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ARP54958_P050
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Datasheets/ManualsPrintable datasheet for anti-UBQLN1 (ARP54958_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationIHC, WB
Additional InformationIHC Information: Human Lung, Respiratory Epithelium (formalin-fixed, paraffin-embedded) stained with UBQLN1 antibody ARP54958_P050 followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the middle region of human UBQLN1
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 92%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 79%
Peptide SequenceSynthetic peptide located within the following region: QFGGNPFASLVSNTSSGEGSQPSRTENRDPLPNPWAPQTSQSSSASSGTA
Concentration0.5 mg/ml
Blocking PeptideFor anti-UBQLN1 (ARP54958_P050) antibody is Catalog # AAP54958 (Previous Catalog # AAPP32119)
ReferenceZhang,D., (2008) J. Mol. Biol. 377 (1), 162-180
Gene SymbolUBQLN1
Gene Full NameUbiquilin 1
Alias SymbolsDA41, DSK2, UBQN, XDRP1, PLIC-1
NCBI Gene Id29979
Protein NameUbiquilin-1
Description of TargetUBQLN1 is an ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and it is found in lesions associated with Alzheimer's and Parkinson's disease. Two transcript variants encoding different isoforms have been found for this gene.This gene encodes an ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and is found in lesions associated with Alzheimer's and Parkinson's disease. Two transcript variants encoding different isoforms have been found for this gene.
Uniprot IDQ5T6J9
Protein Accession #NP_038466
Nucleotide Accession #NM_013438
Protein Size (# AA)589
Molecular Weight62kDa
Protein InteractionsMLLT6; MCM7; IL6ST; IGLC1; IGL; SLC29A2; HK2; GYPB; GRM2; GPX3; GABRD; FN1; FKBP2; FCGR2A; DEFA6; CTAG1B; CSTF2; COL10A1; COL1A2; CALU; IGLV2-14; FAM127B; CSTF2T; FAM127C; TMEM31; AGR3; ITPRIPL1; TRIM32; ACOT7; PLA2G16; SMR3B; AGR2; PSMD6; NUPL1; IST1; LI
  1. What is the species homology for "UBQLN1 Antibody - middle region (ARP54958_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish".

  2. How long will it take to receive "UBQLN1 Antibody - middle region (ARP54958_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "UBQLN1 Antibody - middle region (ARP54958_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "UBQLN1 Antibody - middle region (ARP54958_P050)"?

    This target may also be called "DA41, DSK2, UBQN, XDRP1, PLIC-1" in publications.

  5. What is the shipping cost for "UBQLN1 Antibody - middle region (ARP54958_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "UBQLN1 Antibody - middle region (ARP54958_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "UBQLN1 Antibody - middle region (ARP54958_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "62kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "UBQLN1 Antibody - middle region (ARP54958_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "UBQLN1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "UBQLN1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "UBQLN1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "UBQLN1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "UBQLN1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "UBQLN1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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