Ubiquilin1 Antibody - middle region (OAAB15810)

Catalog No: OAAB15810

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Western blot analysis of anti-Ubiquilin1 Antibody (Center) (Cat.#OAAB15810) in K562 cell line lysates (35ug/lane). Ubiquilin1 (arrow) was detected using the purified Pab.

Western blot analysis of Ubiquilin1 (arrow) using Ubiquilin1 Antibody (Center) (Cat.#OAAB15810). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the UBQLN1 gene (Lane 2) (Origene Technologies).

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat
• Product Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Clonality: Polyclonal
• Isotype: Ig
• Host: Rabbit
• Application: WB, IHC
• Additional Information: Precautions: Ubiquilin1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
  Function: Links CD47 to the cytoskeleton. Promotes the surface expression of GABA-A receptors (By similarity). Promotes the accumulation of uncleaved PSEN1 and PSEN2 by stimulating their biosynthesis. Has no effect on PSEN1 and PSEN2 degradation
  Cellular Location: Cytoplasm. Nucleus.
  Tissue Location: Ubiquitous. Highly expressed throughout the brain; detected in neurons and in neuropathological lesions, such as neurofibrillary tangles and Lewy bodies. Highly expressed in heart, placenta, pancreas, lung, liver, skeletal muscle and kidney
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This Ubiquilin1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-326 amino acids from the Central region of human Ubiquilin1.
• Predicted Homology Based on Immunogen Sequence: Human; Mouse; Rat
• Concentration: Approximately 0.5mg/ml. Actual concentration varies with each lot.
• Application Info: IF: 1:100
  WB: 1:1000
  IHC-P: 1:50~100

Target Info

• Gene Symbol: UBQLN1
• Alias Symbols: DA41, DSK2, UBQN, XDRP1, PLIC-1
• NCBI Gene Id: 29979
• Protein Name: Ubiquilin-1
• Description of Target: Purified Rabbit Polyclonal Antibody (Pab)
• Uniprot ID: Q9UMX0
• Protein Accession #: NP_038466.2
• Molecular Weight: 62519 Da