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- $55: Antibody & Protein in US
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| Datasheets/Manuals | Printable datasheet for UBE2S Antibody (OACA09222) (OACA09222) |
|---|
| Predicted Species Reactivity | Human |
|---|---|
| Product Format | Liquid |
| Clonality | Polyclonal |
| Isotype | IgG |
| Host | Rabbit |
| Conjugation | Unconjugated |
| Application | Enzyme-linked immunosorbent assay|Immunohistochemistry |
| Reconstitution and Storage | -20°C or -80°C |
| Immunogen | Recombinant Human Ubiquitin-conjugating enzyme E2 S protein (1-222AA) |
| Purification | Affinity Purified |
| Preservative | 0.02% sodium azide |
| Formulation | PBS with, 50% glycerol, pH7.3. |
| Gene Symbol | UBE2S |
|---|---|
| Gene Full Name | ubiquitin conjugating enzyme E2 S |
| Alias Symbols | E2 ubiquitin-conjugating enzyme S;E2EPF;E2-EPF;E2-EPF5;EPF5;ubiquitin carrier protein S;ubiquitin conjugating enzyme E2S;ubiquitin-conjugating enzyme E2 S;ubiquitin-conjugating enzyme E2-24 kDa;ubiquitin-conjugating enzyme E2-EPF5;ubiquitin-protein ligase S. |
| NCBI Gene Id | 27338 |
| Protein Name | Ubiquitin-conjugating enzyme E2 S |
| Description of Target | Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins (PubMed:22496338). Catalyzes 'Lys-11'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by specifically elongating 'Lys-11'-linked polyubiquitin chains initiated by the E2 enzyme UBE2C/UBCH10 on APC/C substrates, enhancing the degradation of APC/C substrates by the proteasome and promoting mitotic exit (PubMed:19820702, PubMed:19822757, PubMed:27259151). Also acts by elongating ubiquitin chains initiated by the E2 enzyme UBE2D1/UBCH5 in vitro; it is however unclear whether UBE2D1/UBCH5 acts as an E2 enzyme for the APC/C in vivo. Also involved in ubiquitination and subsequent degradation of VHL, resulting in an accumulation of HIF1A (PubMed:16819549). In vitro able to promote polyubiquitination using all 7 ubiquitin Lys residues, except 'Lys-48'-linked polyubiquitination (PubMed:20061386, PubMed:20622874). |
| Uniprot ID | Q16763 |
| Protein Accession # | NP_055316 |
| Nucleotide Accession # | NM_014501 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "UBE2S Antibody (OACA09222)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
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How long will it take to receive "UBE2S Antibody (OACA09222)"?
This item is available "Domestic: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks | International: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks".
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What buffer format is "UBE2S Antibody (OACA09222)" provided in?
This item is provided in "Liquid".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "UBE2S Antibody (OACA09222)"?
This target may also be called "E2 ubiquitin-conjugating enzyme S;E2EPF;E2-EPF;E2-EPF5;EPF5;ubiquitin carrier protein S;ubiquitin conjugating enzyme E2S;ubiquitin-conjugating enzyme E2 S;ubiquitin-conjugating enzyme E2-24 kDa;ubiquitin-conjugating enzyme E2-EPF5;ubiquitin-protein ligase S." in publications.
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What is the shipping cost for "UBE2S Antibody (OACA09222)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "UBE2S Antibody (OACA09222)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "UBE2S Antibody (OACA09222)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "UBE2S Antibody (OACA09222)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "UBE2S"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "UBE2S"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "UBE2S"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "UBE2S"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "UBE2S"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "UBE2S"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
