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Datasheets/Manuals | Printable datasheet for anti-UBE2K (ARP58011_P050) antibody |
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Tested Species Reactivity | Human |
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Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish |
Product Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Clonality | Polyclonal |
Host | Rabbit |
Application | WB |
Reconstitution and Storage | For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Immunogen | The immunogen is a synthetic peptide directed towards the N terminal region of human UBE2K |
Purification | Affinity Purified |
Predicted Homology Based on Immunogen Sequence | Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 100%; Zebrafish: 100% |
Peptide Sequence | Synthetic peptide located within the following region: FTELRGEIAGPPDTPYEGGRYQLEIKIPETYPFNPPKVRFITKIWHPNIS |
Concentration | 0.5 mg/ml |
Blocking Peptide | For anti-UBE2K (ARP58011_P050) antibody is Catalog # AAP58011 (Previous Catalog # AAPP32434) |
Reference | Christensen,D.E., (2007) Nat. Struct. Mol. Biol. 14 (10), 941-948 |
Publications | Fromm-Dornieden, C. et al. Novel polysome messages and changes in translational activity appear after induction of adipogenesis in 3T3-L1 cells. BMC Mol. Biol. 13, 9 (2012). 22436005 |
Gene Symbol | UBE2K |
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Gene Full Name | Ubiquitin-conjugating enzyme E2K |
Alias Symbols | LIG, HIP2, HYPG, UBC1, E2-25K |
NCBI Gene Id | 3093 |
Protein Name | Ubiquitin-conjugating enzyme E2 K |
Description of Target | UBE2K belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation.The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene. |
Uniprot ID | P61086 |
Protein Accession # | NP_005330 |
Nucleotide Accession # | NM_005339 |
Protein Size (# AA) | 200 |
Molecular Weight | 22kDa |
Protein Interactions | DDI1; DTX3; MIPOL1; TRIM39; ANAPC11; RNF138; SIAH1; RNF5; REL; FZR1; UBC; UBA1; MARCH7; AMFR; TP53; MDM2; BAG3; PRRG4; IQCB1; HTT; CDC6; WDR1; TYMS; TXN; TXNDC17; WDR61; ITCH; NEDD4L; WWP2; NXF1; NUB1; PIAS4; CASP12; SUMO1; SUMO2; DIABLO; UBE2I; CCNB1; BR |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "UBE2K Antibody - N-terminal region (ARP58011_P050)"?
The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish".
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How long will it take to receive "UBE2K Antibody - N-terminal region (ARP58011_P050)"?
This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".
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What buffer format is "UBE2K Antibody - N-terminal region (ARP58011_P050)" provided in?
This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "UBE2K Antibody - N-terminal region (ARP58011_P050)"?
This target may also be called "LIG, HIP2, HYPG, UBC1, E2-25K" in publications.
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What is the shipping cost for "UBE2K Antibody - N-terminal region (ARP58011_P050)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "UBE2K Antibody - N-terminal region (ARP58011_P050)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "UBE2K Antibody - N-terminal region (ARP58011_P050)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "22kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "UBE2K Antibody - N-terminal region (ARP58011_P050)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "UBE2K"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "UBE2K"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "UBE2K"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "UBE2K"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "UBE2K"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "UBE2K"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.