TSPAN33 Antibody - C-terminal region (OAAB05990)

Catalog No: OAAB05990

Size:400UL

Western blot analysis of TSPAN33 Antibody (C-term) in T47D cell lysates (35ug/lane). TSPAN33 (arrow) was detected using the purified Pab.

Formalin-fixed and paraffin-embedded human colon carcinoma reacted with TSPAN33 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Product Info

• Predicted Species Reactivity: Bovine|Human|Mouse
• Product Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Clonality: Polyclonal
• Isotype: Rabbit Ig
• Host: Rabbit
• Application: FC,IHC-P,WB
  Description: This TSPAN33 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 254~283 amino acids from the C-terminal region of human TSPAN33.
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This TSPAN33 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 254-283 amino acids from the C-terminal region of human TSPAN33.
• Predicted Homology Based on Immunogen Sequence: Human
• Concentration: Approximately 0.5mg/ml. Actual concentration varies with each lot.
• Application Info: WB: 1:1000
  IHC-P: 1:50~100
  FC: 1:10~50

Target Info

• Gene Symbol: TSPAN33
• Alias Symbols: 1300010A20Rik, P, Pen, PEN., Penu, penumbra, proerythroblast new membrane, tetraspanin-33, TSPAN-33.
• NCBI Gene Id: 232670|340348|539284
• Protein Name: Tetraspanin-33|tetraspanin-33 [Homo sapiens]
• Description of Target: Plays an important role in normal erythropoiesis (By similarity). It has a role in the differentiation of erythroid progenitors (By similarity). Regulates maturation and trafficking of the transmembrane metalloprotease ADAM10 (PubMed:26686862). Negatively regulates ligand-induced Notch activity probably by regulating ADAM10 activity (PubMed:26686862).|Plays an important role in normal erythropoiesis (PubMed:17158226). It has a role in the differentiation of erythroid progenitors (PubMed:17158226). Regulates maturation and trafficking of the transmembrane metalloprotease ADAM10 (PubMed:23035126). Negatively regulates ligand-induced Notch activity probably by regulating ADAM10 activity (By similarity).|Plays an important role in normal erythropoiesis. It has a role in the differentiation of erythroid progenitors (By similarity). Regulates maturation and trafficking of the transmembrane metalloprotease ADAM10. Negatively regulates ligand-induced Notch activity probably by regulating ADAM10 activity.
• Uniprot ID: Q3SYV5|Q86UF1|Q8R3S2
• Protein Accession #: https://www.ncbi.nlm.nih.gov/protein/NP_848657.1
• Molecular Weight: 31538