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TSG101 Antibody - middle region : FITC (ARP74313_P050-FITC)

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100 ul
$289.00
In Stock
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Conjugation Options

ARP74313_P050 Unconjugated

ARP74313_P050-HRP Conjugated

ARP74313_P050-Biotin Conjugated

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Gene Symbol:
TSG101
Official Gene Full Name:
tumor susceptibility 101
NCBI Gene Id:
7251
Protein Name:
tumor susceptibility gene 101 protein
Swissprot Id:
Q99816-2
Alias Symbols:
TSG10, VPS23
Description of Target:
The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.
Protein Size (# AA):
285
Molecular Weight:
31kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity purified
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express TSG101.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express TSG101.
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of Human TS101
Predicted Species Reactivity:
Human
Peptide Sequence:
Synthetic peptide located within the following region: TGPPNTSYMPGMPGGISPYPSGYPPNPSGYPGCPYPPGGPYPATTSSQYP
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution and Storage:
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Concentration:
1 mg/ml
Protein Interactions:
USHBP1; CEP55; VPS37C; VPS28; AATF; MGRN1; PDLIM7; TAX1BP1; KRT31; KRT13; KIFC3; DAPK3; AR; FAM9B; VPS37A; HAUS1; SYCE1; UBC; LRSAM1; ADRB2; MVB12A; UBAP1; CDKN1A; HGS; gag; gag-pol; GRB2; CDS2; ZFYVE9; VCP; VPS37B; WDR12; XPO1; UBD; ARRDC1; KCNN4; RAB11F
Blocking Peptide:
For anti-TSG101 (ARP74313_P050-FITC) antibody is Catalog # AAP74313
Datasheets/Manuals:
Printable datasheet for anti-TSG101 (ARP74313_P050-FITC) antibody
Conjugation:
FITC (FAM): Excitation 495 nm/ Emission 520 nm
Target Reference:
N/A

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